DACURONIUM

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C33H58N2O3
Molecular Weight	530.8252
Optical Activity	UNSPECIFIED
Defined Stereocenters	10 / 10
E/Z Centers	0
Charge	2

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12C[C@@H]([C@H](O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])CC[C@@]4([H])C[C@H](OC(C)=O)[C@H](C[C@]34C)[N+]5(C)CCCCC5)[N+]6(C)CCCCC6

InChI

InChIKey=XQFBAGUGBNQLRT-ZZZJANDJSA-N

InChI=1S/C33H58N2O3/c1-23(36)38-30-20-24-12-13-25-26(33(24,3)22-29(30)35(5)18-10-7-11-19-35)14-15-32(2)27(25)21-28(31(32)37)34(4)16-8-6-9-17-34/h24-31,37H,6-22H2,1-5H3/q+2/t24-,25+,26-,27-,28-,29-,30-,31-,32-,33-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C33H57N2O3
Molecular Weight	529.8173
Charge	1
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	10 / 10
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4252525 | https://www.ncbi.nlm.nih.gov/pubmed/937668

Dacuronium is an aminosteroid, acting as a competitive antagonist of nicotinic acetylcholine receptors. In animals, dacuronium worked as a short-acting muscle relaxant with a rapid onset of action. In a clinical trial, dacuronium was markedly less potent than tubocurarine and did not show a rapid recovery from its action.

Approval Year

PubMed

Title	Date	PubMed
Some effects of the steroidal muscle relaxant, dacuronium bromide, in anaesthetized patients.	1971 Apr	4252525

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:31:07 GMT 2023` Edited by `admin` on `Fri Dec 15 16:31:07 GMT 2023`
Record UNII	VD6L56ZVX1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DACURONIUM

Common Name

English

DACURONIUM ION

Common Name

English

17-HYDROXYPANCURONIUM

Common Name

English

PANCURONIUM BROMIDE RELATED COMPOUND C

Common Name

English

DACURONIUM CATION

Common Name

English

3.ALPHA.,17.BETA.-DIHYDROXY-5.ALPHA.-ANDROSTAN-2.BETA.,16.BETA.-YLENE)BIS-(1-METHYLPIPERIDINIUM) 3-ACETATE

Common Name

English

PANCURONIUM BROMIDE RELATED COMPOUND C [USP-RS]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29696