DACURONIUM BROMIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C33H58N2O3.2Br
Molecular Weight	690.633
Optical Activity	UNSPECIFIED
Defined Stereocenters	10 / 12
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Br-].[Br-].CC(=O)O[C@H]1C[C@@H]2CC[C@H]3[C@@H]4C[C@@H]([C@H](O)[C@@]4(C)CC[C@@H]3[C@@]2(C)C[C@@H]1[N+]5(C)CCCCC5)[N+]6(C)CCCCC6

InChI

InChIKey=SUKULMJPMHYWKC-GMMLHHOXSA-L

InChI=1S/C33H58N2O3.2BrH/c1-23(36)38-30-20-24-12-13-25-26(33(24,3)22-29(30)35(5)18-10-7-11-19-35)14-15-32(2)27(25)21-28(31(32)37)34(4)16-8-6-9-17-34;;/h24-31,37H,6-22H2,1-5H3;2*1H/q+2;;/p-2/t24-,25+,26-,27-,28-,29-,30-,31-,32-,33-;;/m0../s1

HIDE SMILES / InChI

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C33H57N2O3
Molecular Weight	529.8173
Charge	1
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	10 / 12
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4252525 | https://www.ncbi.nlm.nih.gov/pubmed/937668

Dacuronium is an aminosteroid, acting as a competitive antagonist of nicotinic acetylcholine receptors. In animals, dacuronium worked as a short-acting muscle relaxant with a rapid onset of action. In a clinical trial, dacuronium was markedly less potent than tubocurarine and did not show a rapid recovery from its action.

Approval Year

PubMed

Title	Date	PubMed
Anticholinergic actions of steroid muscle relaxants.	1976-03	937668
Some effects of the steroidal muscle relaxant, dacuronium bromide, in anaesthetized patients.	1971-04	4252525

Substance Class	Chemical Created by `admin` on `Wed Apr 02 07:36:13 GMT 2025` Edited by `admin` on `Wed Apr 02 07:36:13 GMT 2025`
Record UNII	33482245B6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NB 68

Preferred Name

English

DACURONIUM BROMIDE

Official Name

English

NB-68

Code

English

3.ALPHA.,17.BETA.-DIHYDROXY-5.ALPHA.-ANDROSTAN-2.BETA.,16.BETA.-YLENE)BIS-(1-METHYLPIPERIDINIUM)DIBROMIDE 3-ACETATE

Common Name

English

dacuronium bromide [INN]

Common Name

English

PANCURONIUM BROMIDE IMPURITY A [EP IMPURITY]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29696