Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C7H11NO4S |
| Molecular Weight | 205.232 |
| Optical Activity | ( - ) |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)N[C@@H](CSC(C)=O)C(O)=O
InChI
InChIKey=HSPYGHDTVQJUDE-LURJTMIESA-N
InChI=1S/C7H11NO4S/c1-4(9)8-6(7(11)12)3-13-5(2)10/h6H,3H2,1-2H3,(H,8,9)(H,11,12)/t6-/m0/s1
| Molecular Formula | C7H11NO4S |
| Molecular Weight | 205.232 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Dacisteine is a derivative of a N-acetylcysteine, where a second acetyl group is attached to a sulfur atom. Dacisteine is marketed in France under tradename Mucothiol for the treatment of disorders of bronchial secretion, acute bronchitis and acute episode of chronic bronchopneumopathies. Dacisteine exerts its action on the gel phase of the mucus, presumably by breaking the disulfide bonds of the glycoproteins, and thus promotes the expectoration.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Double-prodrugs of L-cysteine: differential protection against acetaminophen-induced hepatotoxicity in mice. | 2002 |
|
| Reactions of purines-containing butenolides with L-cysteine or N-acetyl-L-cysteine as model biological nucleophiles: a potent mechanism-based inhibitor of ribonucleotide reductase caused apoptosis in breast carcinoma MCF7 cells. | 2002 Mar |
|
| First total synthesis of mycothiol and mycothiol disulfide. | 2004 Feb 5 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:31:39 GMT 2025
by
admin
on
Mon Mar 31 18:31:39 GMT 2025
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| Record UNII |
WF970ATW3T
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| Record Status |
Validated (UNII)
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NCI_THESAURUS |
C74536
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242-537-5
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65690
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DTXSID00172034
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SUB06884MIG
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WF970ATW3T
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100000083972
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1760
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C74266
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5346
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| Related Record | Type | Details | ||
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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PARENT -> IMPURITY |
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ACTIVE MOIETY |
