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Showing 1 - 10 of 17 results

Status:
US Approved Rx (2011)
First approved in 2011

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Vandetanib, 4-anilinoquinazoline, is an anti-cancer drug that with the potential for use in a broad range of tumour types. In 2011 vandetanib (trade name Caprelsa) was approved by the FDA to treat nonresectable, locally advanced, or metastatic medull...
Status:
US Approved Rx (2011)
First approved in 1991

Class (Stereo):
CHEMICAL (ACHIRAL)



Nabumetone is a naphthylalkanone. Is is a non-selective prostaglandin G/H synthase (a.k.a. cyclooxygenase or COX) inhibitor that acts on both prostaglandin G/H synthase 1 and 2 (COX-1 and -2). Prostaglandin G/H synthase catalyzes the conversion of ar...
Status:
US Approved Rx (2000)
First approved in 1983

Class (Stereo):
CHEMICAL (ACHIRAL)



Ranitidine, a histamine H2-receptor antagonist, is now well established as a potent inhibitor of gastric acid secretion effective in the treatment and prophylaxis of gastrointestinal lesions aggravated by gastric acid secretion.
Status:
US Approved Rx (2009)
First approved in 1961

Class (Stereo):
CHEMICAL (RACEMIC)



Glycopyrrolate is a synthetic anticholinergic agent with a quaternary ammonium structure. Glycopyrrolate is a muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with s...
Status:
US Approved Rx (2024)
First approved in 2024

Class (Stereo):
CHEMICAL (ACHIRAL)



Xanomeline (LY-246,708) is an orthosteric muscarinic acetylcholine receptor (mAChR) agonist, often referred to as M1/M4-preferring. It is also known to act as a M5 receptor antagonist. Xanomeline was studied in clinical trials phase I in schizophreni...
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)



AMG-487 is a potent and selective orally bioavailable chemokine (C-X-C motif) receptor 3 (CXCR3) antagonist that displays dose- and time-dependent pharmacokinetics in human subjects after multiple oral dosing. AMG-487 is an 8-azaquinazolinone, it can...
Status:
US Approved Rx (2000)
First approved in 1983

Class (Stereo):
CHEMICAL (ACHIRAL)



Ranitidine, a histamine H2-receptor antagonist, is now well established as a potent inhibitor of gastric acid secretion effective in the treatment and prophylaxis of gastrointestinal lesions aggravated by gastric acid secretion.
Status:
US Approved Rx (2000)
First approved in 1983

Class (Stereo):
CHEMICAL (ACHIRAL)



Ranitidine, a histamine H2-receptor antagonist, is now well established as a potent inhibitor of gastric acid secretion effective in the treatment and prophylaxis of gastrointestinal lesions aggravated by gastric acid secretion.
Status:
US Approved Rx (2009)
First approved in 1961

Class (Stereo):
CHEMICAL (ABSOLUTE)



Glycopyrrolate is a synthetic anticholinergic agent with a quaternary ammonium structure. Glycopyrrolate is a muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with s...
Status:
US Approved Rx (2009)
First approved in 1961

Class (Stereo):
CHEMICAL (ABSOLUTE)



Glycopyrrolate is a synthetic anticholinergic agent with a quaternary ammonium structure. Glycopyrrolate is a muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with s...

Showing 1 - 10 of 17 results