U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 2781 - 2790 of 141793 results

Status:
Investigational
Source:
INN:etaminile [INN]
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Etaminile is an antitussive agent.
Status:
Investigational
Source:
INN:mibolerone
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Mibolerone is a synthetic anabolic steroid. It binds both androgen and progesterone receptors and exerts both androgenic and progestagenic actions. Mibolerone (CHEQUE® Drops) was used in veterinary for estrous (heat) prevention in adult female dogs not intended primarily for breeding purposes. No prescription preparation, human or veterinary, is currently known to contain mibolerone worldwide.
Status:
Investigational
Source:
INN:clodoxopone [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Clodoxopone (LR 19731) is a hypoglycemic agent, developed in the 1980s by Italian company Lusofarmaco. In animal models, the drug lowered the plasma cholesterol and triglyceride levels in several experimental conditions after single or repeated treatments. Results of the clinical trials of the drug are not reported.
Status:
Investigational
Source:
NCT00244751: Phase 2 Interventional Completed Cirrhosis, Liver
(2005)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Farglitazar is a non-thiazolidinedione insulin sensitizer and agonist of peroxisome proliferator-activated receptor-gamma. GlaxoSmithKline was developing farglitazar for the treatment of liver fibrosis and Type 2 diabetes mellitus.
Status:
Investigational
Source:
INN:evernimicin
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Evernimicin (SCH 27899) is an oligosaccharide antibiotic. It nteracts with the large ribosomal subunit (50S) and inhibits bacterial protein synthesis. Evernimicin exerts activity against a wide spectrum of gram-positive bacteria and activity against some gram-negative bacteria. Evernimicin was being studied for the treatment of susceptible bacterial infections however its development has been discontinued.
Status:
Investigational
Source:
INN:cinoxolone
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Cinoxolone is a derivative of glycyrrhetinic acid. Is is claimed to possess antiulcer properties.
Status:
Investigational
Source:
INN:metrafazoline
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Metoxepin was developed as an antiemetic, neuroleptic and antihistamine agent. This drug has never been marketed.
Status:
Investigational
Source:
INN:barixibat [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:mofegiline
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Mofegiline (MDL 72,974A or (E)-2-(4-fluorophenethyl)-3-fluoroallylamine, hydrochloride), is a selective and irreversible inhibitor of monoamine oxidase type B (MAO-B) both in vitro and in vivo. In addition, mofegiline inhibits semicarbazide-sensitive amine oxidase activity from human serum and saphenous vein. In phase II studies, MDL 72,974A is proving to be a useful adjunct to conventional therapy of Parkinson's disease. It seems mofegiline development was discontinued.
Status:
Investigational
Source:
INN:resorantel
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Resorantel (HOE 296V) is an anthelmintic agent. Resorantel was found to be highly effective against Houttuynia struthionis (a tapeworm, parasite of the small intestine) in ostriches. Resorantel also showed anthelmintic efficacy against Thysaniezia giardi and Avitellina spp. (both tapeworms) when tested in sheep. Similar results have been found in goats and cattle.

Showing 2781 - 2790 of 141793 results