RESORANTEL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H10BrNO3
Molecular Weight	308.127
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC=CC(O)=C1C(=O)NC2=CC=C(Br)C=C2

InChI

InChIKey=IHYNKGRWCDKNEG-UHFFFAOYSA-N

InChI=1S/C13H10BrNO3/c14-8-4-6-9(7-5-8)15-13(18)12-10(16)2-1-3-11(12)17/h1-7,16-17H,(H,15,18)

HIDE SMILES / InChI

Molecular Formula	C13H10BrNO3
Molecular Weight	308.127
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3210222 | https://www.ncbi.nlm.nih.gov/pubmed/3210220 | https://www.ingentaconnect.com/content/sabinet/savet/1970/00000041/00000003/art00022 | https://www.cabdirect.org/cabdirect/abstract/19710802730

Resorantel (HOE 296V) is an anthelmintic agent. Resorantel was found to be highly effective against Houttuynia struthionis (a tapeworm, parasite of the small intestine) in ostriches. Resorantel also showed anthelmintic efficacy against Thysaniezia giardi and Avitellina spp. (both tapeworms) when tested in sheep. Similar results have been found in goats and cattle.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Uniprot: A0A2H1C4Q5 1 Target ID: Uniprot: A0A2H1C4Q5 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4718453	Inhibitor 8297		5.2 µM [IC50]

PubMed

Title	Date	PubMed
Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation.	2003 Jun 3	12756150

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:00:43 GMT 2023` Edited by `admin` on `Sat Dec 16 16:00:43 GMT 2023`
Record UNII	2I8V5Q9A78
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RESORANTEL

Official Name

English

HOE-296-V

Code

English

RESORANTEL [MI]

Common Name

English

HOE 296 V

Code

English

HOE-296 V

Code

English

resorantel [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C250