U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C13H10BrNO3
Molecular Weight 308.127
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RESORANTEL

SMILES

OC1=CC=CC(O)=C1C(=O)NC2=CC=C(Br)C=C2

InChI

InChIKey=IHYNKGRWCDKNEG-UHFFFAOYSA-N
InChI=1S/C13H10BrNO3/c14-8-4-6-9(7-5-8)15-13(18)12-10(16)2-1-3-11(12)17/h1-7,16-17H,(H,15,18)

HIDE SMILES / InChI

Molecular Formula C13H10BrNO3
Molecular Weight 308.127
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Resorantel (HOE 296V) is an anthelmintic agent. Resorantel was found to be highly effective against Houttuynia struthionis (a tapeworm, parasite of the small intestine) in ostriches. Resorantel also showed anthelmintic efficacy against Thysaniezia giardi and Avitellina spp. (both tapeworms) when tested in sheep. Similar results have been found in goats and cattle.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
5.2 µM [IC50]
PubMed

PubMed

TitleDatePubMed
Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation.
2003 Jun 3
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:00:43 GMT 2023
Edited
by admin
on Sat Dec 16 16:00:43 GMT 2023
Record UNII
2I8V5Q9A78
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RESORANTEL
INN   MI  
INN  
Official Name English
HOE-296-V
Code English
RESORANTEL [MI]
Common Name English
HOE 296 V
Code English
HOE-296 V
Code English
resorantel [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C250
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
WHO-VATC QP52AG04
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
Code System Code Type Description
MERCK INDEX
m9545
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY Merck Index
CAS
20788-07-2
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY
ECHA (EC/EINECS)
244-040-9
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY
SMS_ID
100000080552
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105347
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY
PUBCHEM
65696
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY
EPA CompTox
DTXSID80174879
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY
NCI_THESAURUS
C72144
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY
FDA UNII
2I8V5Q9A78
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY
MESH
C000982
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY
INN
2712
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY
EVMPD
SUB10288MIG
Created by admin on Sat Dec 16 16:00:43 GMT 2023 , Edited by admin on Sat Dec 16 16:00:43 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY