CLODOXOPONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H21ClN2O3
Molecular Weight	384.856
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=CC=C(C=C1)C2=C(CCN3CCN(CC3)C4=CC=CC=C4)OC(=O)O2

InChI

InChIKey=QPIRWBYRKYGHDQ-UHFFFAOYSA-N

InChI=1S/C21H21ClN2O3/c22-17-8-6-16(7-9-17)20-19(26-21(25)27-20)10-11-23-12-14-24(15-13-23)18-4-2-1-3-5-18/h1-9H,10-15H2

HIDE SMILES / InChI

Molecular Formula	C21H21ClN2O3
Molecular Weight	384.856
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7255538

Clodoxopone (LR 19731) is a hypoglycemic agent, developed in the 1980s by Italian company Lusofarmaco. In animal models, the drug lowered the plasma cholesterol and triglyceride levels in several experimental conditions after single or repeated treatments. Results of the clinical trials of the drug are not reported.

Approval Year

PubMed

Title	Date	PubMed
N-phenylpiperazine derivatives with hypocholesterolemic activity.	1985 Jun	4009605

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:02:44 GMT 2023` Edited by `admin` on `Sat Dec 16 16:02:44 GMT 2023`
Record UNII	F94O7Q5JLM
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLODOXOPONE

Official Name

English

4-(P-CHLOROPHENYL)-5-(2-(4-PHENYL-1-PIPERAZINYL)ETHYL)-1,3-DIOXOL-2-ONE

Common Name

English

clodoxopone [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29703