5-Fluoroorotic acid is a fluorinated derivative of the pyrimidine precursor orotic acid. 5-Fluoroorotic acid exert considerable antitumor activity against transplanted tumors in rats and mice. 5-Fluoroorotate shows increased cytotoxicity on ovarian carcinoma cell lines following encapsulation in liposomes. 5-Fluoroorotic acid is used in vitro in the positive selection of genetically transformed yeast cells.

Methylparaben (E number E218) is preservative in the food, cosmetic, and pharmaceutical industries. It is completely absorbed through the skin or after ingestion and and it is hydrolyzed to para-hydroxybenzoic acid, and metabolites are rapidly excreted in the urine. Methylparaben is on the FDA generally regarded as safe list.

Potassium Orotate is a non-steroidal anabolic preparation with regenerating, diuretic effect. Potassium Orotate improves appetite, cardiac glycosides tolerance, stimulates regenerative and reparative processes of metabolism. Orotic acid is one of precursors the pyrimidine nucleotides which are a part of nucleic acids which participate in synthesis of protein molecules. In this regard potassium orotate is applied as substance of anabolic action at disturbances of protein metabolism, first of all at disturbance of albumin function of a liver, at the dystrophic changes in a myocardium which developed as owing to pathological process (a myocarditis, myocardial infarction), and as a result of a physical overstrain in sport as the general stimulators of metabolic processes.

Methylparaben (E number E218) is preservative in the food, cosmetic, and pharmaceutical industries. It is completely absorbed through the skin or after ingestion and and it is hydrolyzed to para-hydroxybenzoic acid, and metabolites are rapidly excreted in the urine. Methylparaben is on the FDA generally regarded as safe list.