Trolox (6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) is a synthetic Vitamin E analog exerting antioxidant properties. Trolox is widely used for estimation of antioxidant capacity in the assay based on electron transfer reaction. Trolox-equivalent antioxidant capacity (TEAC) assay is based on the suppression of the absorbance of radical cations of 2,2′-azinobis(3-ethylbenzothiazoline 6-sulfonate) (ABTS) by antioxidants in the test sample when ABTS incubates with a peroxidase (metmyoglobin) and hydrogen peroxide.

S-ETHYLCYSTEINE is hydrophilic cysteine-containing compound naturally synthesized in many Allium plant foods such as garlic and onion. Dietary intake of S-Ethyl-L-cysteine displayed anti-oxidative and anti-inflammatory protection against ethanol-induced liver injury in mice. S-Ethyl-L-cysteine ameliorated H2O2-induced apoptotic, oxidative and inflammatory injury in human BEAS-2B cells (bronchial cells) through preserving Bcl-2 expression, decreasing ROS formation and limiting protein expression of NAPDH oxidase, NF-kB, and MAPK. S-Ethyl-L-cysteine is used as the chiral reagent.

Nocardamine is a cyclic trihydroxamate. It belongs to a group of microbial siderophores which form complexes with iron and aluminum ions. Nocardamine was described first as an antibiotic active against mycobacteria and proteus. It is produced by Nocardia species, several Streptomyces species, Chromobacterium and Pseudomonas. Nocardamine exhibited significant antioxidant effects. It is suggested that it should be applied in food and biological model systems. In vitro nocardamine showed antitumor activity – it has inhibitory effects to colony formation of tumor cells.

Datiscetin is a yellow plant dye from the flavonol group. It exhibited inhibitory activity against methicillin-resistant Staphylococcus aureus (MRSA). Datiscetin demonstrated antioxidant activity – it inhibits CCl4-induced microsomal lipid peroxidation and behaved as potent scavenger of the superoxide anion radicals. Datiscetin activated the human constitutive androstane receptor. It inhibited amyloid beta-42 protein aggregation. Datiscetin interacts with amyloid beta-42 protein directly, with monomers and small aggregates.

(1R,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (MTCA) is a β-carboline indole alkaloid naturally occurring in plants, foods, insects, and endogenously in mammals and humans. It exerts antioxidant and antithrombotic properties. MTCA is thought to be a possible causative substance of eosinophilia-myalgia syndrome associated with ingestion of L-tryptophan.

Oridonin is a diterpenoid purified from Rabdosia rubescens. In traditional Chinese medicine oridonin powder (Donglingcao herb extract) is used as an over-the-counter medicine because of its anti-tumor, anti-bacterial, anti-inflammatory, analgesic and other effects. Oridonin was shown to inhibit many tumor cell lines in vitro and its mechanism of action is mainly explained by inhibition of NF-kB signaling, Keap1-Nrf2-ARE pathway and upregulation of p53/p21 signaling and ROS production.

Zinc Nicotinate is a mineral powder that is essential for the immune system, enzymes, hormones, the reproductive system, and the skeletal system. It is a functional food nutritional ingredient.