CAFTARIC ACID

O[C@H]([C@@H](OC(=O)\C=C\C1=CC(O)=C(O)C=C1)C(O)=O)C(O)=O

InChIKey=SWGKAHCIOQPKFW-JTNORFRNSA-N

InChI=1S/C13H12O9/c14-7-3-1-6(5-8(7)15)2-4-9(16)22-11(13(20)21)10(17)12(18)19/h1-5,10-11,14-15,17H,(H,18,19)(H,20,21)/b4-2+/t10-,11-/m1/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	1
Optical Activity	UNSPECIFIED

Targets

Primary Target	Pharmacology	Potency
Oxidative Stress 160 Target ID: WP173 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30821252 \| https://www.ncbi.nlm.nih.gov/pubmed/29148979	Inhibitor 8297
apoptotic process 48 Target ID: GO:0006915 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29148979	Inhibitor 8297
inflammatory response 47 Target ID: GO:0006954 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30821252	Inhibitor 8297
Botulinum neurotoxin type A 3 Target ID: CHEMBL5344 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20158239	Inhibitor 8297
Tyrosine-protein kinase Lck 2 Target ID: P06239\|\|\|Q96DW4 Gene ID: 3932.0 Gene Symbol: LCK Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/19427202	Inhibitor 8297	118.0 µM [IC50]
Proto-oncogene tyrosine-protein kinase Src 7 Target ID: P12931 Gene ID: 6714.0 Gene Symbol: SRC Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/19427202	Inhibitor 8297	74.0 µM [IC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:32:12 GMT 2023` Edited by `admin` on `Sat Dec 16 08:32:12 GMT 2023`
Record UNII	WCV7W3174L
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

CAFTARIC ACID

Common Name

English

CAFTARIC ACID (CONSTITUENT OF ECHINACEA ANGUSTIFOLIA ROOT, ECHINACEA PALLIDA ROOT, ECHINACEA PURPUREA ROOT AND ECHINACEA PURPUREA AERIAL PARTS) [DSC]

Common Name

English

TRANS-CAFTARIC ACID

Common Name

English

(2R,3R)-2-(((2E)-3-(3,4-DIHYDROXYPHENYL)-2-PROPENOYL)OXY)-3-HYDROXYSUCCINIC ACID

Systematic Name

English

BUTANEDIOIC ACID, 2-(((2E)-3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPEN-1-YL)OXY)-3-HYDROXY-, (2R,3R)-

Systematic Name

English

CAFTARIC ACID [USP-RS]

Common Name

English

Code System Code Type Description

WIKIPEDIA

Caftaric acid