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Showing 1 - 10 of 62 results

Status:
US Approved Rx (2005)
First approved in 2000

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodiu...
Status:
US Approved Rx (2018)
First approved in 1997

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pramipexole is a nonergot dopamine agonist with high relative in vitro specificity and full intrinsic activity at the D2 subfamily of dopamine receptors, binding with higher affinity to D3 than to D2 or D4 receptor subtypes. The relevance of D3 recep...
Status:
US Approved Rx (1982)
First approved in 1966

Class (Stereo):
CHEMICAL (ACHIRAL)



Furosemide, a sulfonamide-type loop diuretic structurally related to bumetanide, is used to manage hypertension and edema associated with congestive heart failure, cirrhosis, and renal disease, including the nephrotic syndrome. Furosemide inhibits wa...
Status:
US Approved Rx (1993)
First approved in 1959

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Metha...
Status:
US Approved Rx (2024)
First approved in 1958

Class (Stereo):
CHEMICAL (ACHIRAL)



Like other thiazides, chlorothiazide promotes water loss from the body (diuretics). It inhibits Na /Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazid...
Status:
US Approved Rx (1979)
First approved in 1957

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Methocarbamol is a central muscle relaxant for skeletal muscles, used to treat spasms. It is structurally related to guaifenesin. Methocarbamol's exact mechanism of causing skeletal muscle relaxation is unknown. It is thought to work centrally, perha...
Status:
US Approved Rx (2008)
First approved in 1953

Class (Stereo):
CHEMICAL (ACHIRAL)



Acetazolamide, usually sold under the trade name Diamox in some countries. DIAMOX is used for adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery...
Status:
US Approved Rx (1969)
First approved in 1948

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Mafenide is a sulfonamide-type medication used as an antibiotic. It is indicated for use as an adjunctive topical antimicrobial agent to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. Mafeni...
Status:
US Approved Rx (2012)
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



Nitrite Ion is a symmetric anion with equal N–O bond lengths. Nitrite is important in biochemistry as a source of the potent vasodilator nitric oxide. Nitrate or nitrite (ingested) under conditions that result in endogenous nitrosation has been class...
Status:
US Approved OTC
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



Diammonium carbonate is a salt with the chemical formula (NH4)2CO3. Since it readily degrades to gaseous ammonia and carbon dioxide upon heating, it is used as a leavening agent and also as smelling salt. Ammonium carbonate may be used as a leavening...