Terbufos (S-tert-butylthiomethyl O,O-diethyl phosphorodithioate), a systemic insecticide, is the fourth most commonly used organophosphate insecticide (OP) in the United States, with an estimated 3 to 5 million pounds applied in 2001. First registered for use in the United States in 1974, terbufos was initially used to control insects and nematodes on corn. Currently, terbufos is also registered for use on sugar beets, sorghum, and bananas; terbufos is not registered for residential use or in public health applications. Terbufos is metabolized and activated to its neurotoxic form via oxidative desulfuration. This active form of terbufos irreversibly inhibits acetylcholinesterase, leading to the accumulation of acetylcholine and the classic signs and symptoms associated with muscarinic and nicotinic receptor overstimulation. The United States Environmental Protection Agency (USEPA) classifies terbufos in toxicity category I (high acute toxicity), but as group E for carcinogenicity (evidence of non-carcinogenicity for humans). This group E carcinogenicity classification is based largely on the lack of carcinogenic effects in two animal studies and lack of mutagenicity in several short-term genotoxicity assays. Primarily formulated as granules, Terbufos is applied at planting in a band or directly to the seed furrow. Terbufos is not approved for use in the European Union.

Hexanamide is an amide of caproic acid. The compound is carcinogenic when administered to mice chronically.

Anthraquinone has yet to be found in nature. Of all the quinones found naturally, those derived from anthraquinone far exceed all others. Many of these are found in molds. Derivatives of 9,10-anthracenedione (anthraquinones) with several hydroxy and other functional groups are biologically active compounds isolated from Rubia and Cassia medical plant species. Anthraquinone is a comparatively safe compound: LD50 (rat) is 3500 mg/kg. It is a mild allergen and, as a fine powder, may cause skin irritation. Exposure to 3,000 ppm may be tolerated for only 30–60 min after which irritation of the nose, throat, and lungs may occur along with headaches, dizziness, and slurred speech. 9,10-anthraquinone is a weak carcinogen. Aside from its major use in the manufacture of intermediates for anthraquinone dyes and pigments, anthraquinone is finding increasing interest as a catalyst in the pulping of wood, in the polymerization of various materials for plastics, and in the isomerization of vegetable oils. It has been used to make seeds distasteful to birds (bird repellent) and as an accelerator in nickel electroplating.

Dichlone is a fungicide without regulatory approval for use in the EU. It has a low aqueous solubility and is not mobile and, based on its chemical properties, it is unlikely to leach to groundwater. It is not persistent in most soil systems. Dichlone has a moderate mammalian toxicity. Dichlone is an inhibitor of the DNA methyltransferase 3A/3L complex.