CYHALOTHRIN

Details

Stereochemistry	MIXED
Molecular Formula	C23H19ClF3NO3
Molecular Weight	449.85
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 3
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1(C)C(\C=C(/Cl)C(F)(F)F)C1C(=O)OC(C#N)C2=CC=CC(OC3=CC=CC=C3)=C2

InChI

InChIKey=ZXQYGBMAQZUVMI-UNOMPAQXSA-N

InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-

HIDE SMILES / InChI

Molecular Formula	C23H19ClF3NO3
Molecular Weight	449.85
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 3
E/Z Centers	1
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
A concentration addition model to assess activation of the pregnane X receptor (PXR) by pesticide mixtures found in the French diet.	2014-09	25028461
Molecular cloning, expression and antioxidant characterisation of a typical thioredoxin gene (AccTrx2) in Apis cerana cerana.	2013-09-15	23747404
The inhibition of major human hepatic cytochrome P450 enzymes by 18 pesticides: comparison of the N-in-one and single substrate approaches.	2013-08	22634058
Influence of pesticides on the pH regulatory enzyme, carbonic anhydrase, from European Seabass liver and bovine erythrocytes.	2012-09	22561108
Involvement of dopaminergic and serotonergic systems in the neurobehavioral toxicity of lambda-cyhalothrin in developing rats.	2012-05-20	22366556
Genotoxicity of pesticide mixtures present in the diet of the French population.	2012-04	22389207
Characterization of human cytochrome P450 induction by pesticides.	2012-03-29	22310298
Antiplasmodial and antitrypanosomal activity of pyrethrins and pyrethroids.	2011-09-14	21786822
Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens.	2011-06	21310686
Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.	2011-02-27	21115097
Assessing hormone receptor activities of pyrethroid insecticides and their metabolites in reporter gene assays.	2010-07	20410157
Integrative assessment of enantioselectivity in endocrine disruption and immunotoxicity of synthetic pyrethroids.	2010-05	20097460
Evidence for a separate mechanism of toxicity for the Type I and the Type II pyrethroid insecticides.	2009-11	19766671
Comparative functional observational battery study of twelve commercial pyrethroid insecticides in male rats following acute oral exposure.	2009-11	19748519
Evidence for dose-additive effects of pyrethroids on motor activity in rats.	2009-10	20019907
An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes.	2009-08	20183062
Pyrethroid insecticides: isoform-dependent hydrolysis, induction of cytochrome P450 3A4 and evidence on the involvement of the pregnane X receptor.	2009-05-15	19249324
Estrogenic activity of lambda-cyhalothrin in the MCF-7 human breast carcinoma cell line.	2008-05	18419197
Structure-activity relationships for the action of 11 pyrethroid insecticides on rat Na v 1.8 sodium channels expressed in Xenopus oocytes.	2006-03-15	16051293
In vitro toxicity of selected pesticides on RTG-2 and RTL-W1 fish cell lines.	2005-05	15734586
Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes.	2004-07-09	15123619
Experimental hut comparisons of nets treated with carbamate or pyrethroid insecticides, washed or unwashed, against pyrethroid-resistant mosquitoes.	2004-06	15189238

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:33:43 GMT 2025` Edited by `admin` on `Mon Mar 31 18:33:43 GMT 2025`
Record UNII	V0V73PEB8M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CYHALOTHRIN

Common Name

English

PP 563

Preferred Name

English

CYHALOTHRIN [HSDB]

Common Name

English

(RS)-.ALPHA.-CYANO-3-PHENOXYBENZYL (Z)-(1RS,3RS)-3-(2-CHLORO-3,3,3-TRIFLUOROPROPENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATE

Systematic Name

English

CYHALOTHRIN [MART.]

Common Name

English

CYHALOTHRIN [ISO]

Common Name

English

CYHALOTHRIN [MI]

Common Name

English

PP-563

Code

English

Classification Tree Code System Code

EPA PESTICIDE CODE

128867