MONOCROTOPHOS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H14NO5P
Molecular Weight	223.1635
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNC(=O)\C=C(/C)OP(=O)(OC)OC

InChI

InChIKey=KRTSDMXIXPKRQR-AATRIKPKSA-N

InChI=1S/C7H14NO5P/c1-6(5-7(9)8-2)13-14(10,11-3)12-4/h5H,1-4H3,(H,8,9)/b6-5+

HIDE SMILES / InChI

Molecular Formula	C7H14NO5P
Molecular Weight	223.1635
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Organophosphate pesticides-induced changes in the redox status of rat tissues and protective effects of antioxidant vitamins.	2015-04	24248738
Effects of monocrotophos pesticide on steroidogenesis and transcription of steroidogenic enzymes in rainbow trout RTG-2 cells involving the protein kinase A signal pathway.	2015-02	25317747
Prolonged monocrotophos intake induces cardiac oxidative stress and myocardial damage in rats.	2013-05-10	23228476
Trans-resveratrol restores the damages induced by organophosphate pesticide-monocrotophos in neuronal cells.	2013-01	23833438
Increased oxidative stress is associated with the development of organophosphate-induced delayed neuropathy.	2012-12	22751200
The effect of acute severe monocrotophos poisoning on inhibition, expression and activity of acetylcholinesterase in different rat brain regions.	2012-10	22903060
Expression and inducibility of cytochrome P450s (CYP1A1, 2B6, 2E1, 3A4) in human cord blood CD34(+) stem cell-derived differentiating neuronal cells.	2012-10	22733800
Insights into the mechanisms mediating hyperglycemic and stressogenic outcomes in rats treated with monocrotophos, an organophosphorus insecticide.	2012-03-29	22305719
Monocrotophos induced oxidative damage associates with severe acetylcholinesterase inhibition in rat brain.	2012-03	22285544
Augmentation of hepatic and renal oxidative stress and disrupted glucose homeostasis by monocrotophos in streptozotocin-induced diabetic rats.	2011-09-30	21821013
Concomitant exposure to arsenic and organophosphates on tissue oxidative stress in rats.	2011-05	21349312
Monocrotophos induced apoptosis in PC12 cells: role of xenobiotic metabolizing cytochrome P450s.	2011-03-21	21445290
Esterase metabolism of cholinesterase inhibitors using rat liver in vitro.	2011-03-15	21237238
Caspase cascade regulated mitochondria mediated apoptosis in monocrotophos exposed PC12 cells.	2010-11-15	20957986
Monocrotophos toxicity and bioenergetics of muscle weakness in the rat.	2010-11-09	20728503
Effects of monocrotophos on the reproductive axis in the male goldfish (Carassius auratus): potential mechanisms underlying vitellogenin induction.	2010-06-01	20149464
Effects of monocrotophos on the reproductive axis in the female goldfish (Carassius auratus).	2010-06	20298809
Effects of combined exposure to dichlorvos and monocrotophos on blood and brain biochemical variables in rats.	2010-02	20026515
Impaired mitochondrial functions in organophosphate induced delayed neuropathy in rats.	2009-12	19517227
Estrogenic effects of monocrotophos evaluated by vitellogenin mRNA and protein induction in male goldfish (Carassius auratus).	2009-08	19439194
A comparative study on the relationship between various toxicological endpoints in Caenorhabditis elegans exposed to organophosphorus insecticides.	2008	18569613
Comparison of pesticide sensitivity by electrochemical test based on acetylcholinesterase biosensor.	2007-09-30	17590326
Mutations in acetylcholinesterase genes of Rhopalosiphum padi resistant to organophosphate and carbamate insecticides.	2007-02	17546082
Effect of pesticide residues on health and different enzyme levels in the blood of farm workers from Gadap (rural area) Karachi-Pakistan.	2006-09	16487989
The "intermediate syndrome" as critical sequelae of organophosphate poisoning: the first report of two cases in Thailand.	2005-09	16536121
Efficacy of trimedoxime in mice poisoned with dichlorvos, heptenophos or monocrotophos.	2005-02	15679473
Effects of organophosphorous pesticides used in china on various mammalian cells.	2005	15793557
Serotonin and benzylamine oxidation by type A and type B MAO of rat brain in presence of organophosphate pesticides.	2001-08	12018584
Reactivation by various oximes of human erythrocyte acetylcholinesterase inhibited by different organophosphorus compounds.	1996	8783813
Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected carbamate and organophosphate insecticides and congeners of carbaryl.	1993-03-01	8349949

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:49:00 GMT 2025` Edited by `admin` on `Mon Mar 31 17:49:00 GMT 2025`
Record UNII	5Q3PE07Z18
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MONOCROTOPHOS

Common Name

English

AZODRIN

Preferred Name

English

MONOCIL

Brand Name

English

KADETT

Brand Name

English

DIMETHYL (1E)-1-METHYL-3-(METHYLAMINO)-3-OXO-1-PROPENYL PHOSPHATE

Systematic Name

English

MONOCRON

Brand Name

English

MONOCROTOPHOS [ISO]

Common Name

English

NUVACRON

Brand Name

English

DIMETHYL (E)-1-METHYL-2-(METHYLCARBAMOYL)VINYL PHOSPHATE

Systematic Name

English

MONOCROTOPHOS [MI]

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

58901