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Development Status

Possibly Marketed Outside US

4

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Primary Target

Alcohol dehydrogenase alpha chain

2

Deoxycytidine kinase

2

L-lactate dehydrogenase A chain

2

NAD-dependent deacetylase sirtuin 1

2

cell redox homeostasis

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Approval Year

2011

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2023

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Condition

Unknown

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CNS Penetrant

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Chemical

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CAS

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ECHA (EC/EINECS)

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EPA CompTox

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Showing 1 - 4 of 4 results

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Doxecitine

0W860991D6

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Status:

Possibly Marketed Outside US

First approved in 2023

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Deoxycytidine kinase

Conditions:

2′-Deoxycytidine (deoxyC) is one of the deoxy nucleosides, which after phosphorylation to dCTP is used to synthesize DNA via various DNA polymerases or reverse transcriptases. Deoxycytidine is phosphorylated by deoxycytidine kinase (dCK). This enzyme...

catalyzes the initial conversion of the nucleosides deoxyadenosine (dA), deoxyguanosine (dG), and deoxycytidine (dC) into their monophosphate forms, with subsequent phosphorylation to the triphosphate forms performed by additional enzymes.

NADH

4J24DQ0916

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Status:

Possibly Marketed Outside US

First approved in 2011

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

cell redox homeostasis

NAD-dependent deacetylase sirtuin 1

L-lactate dehydrogenase A chain

Alcohol dehydrogenase alpha chain

Nicotinamide adenine nucleotide (NAD) is a cofactor found in all living cells. It exists in oxidized form (NAD+) and reduced form (NADH). NADH is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron...

carrier by being alternately oxidized (NAD+) and reduced (NADH). NADH supplements are used for improving mental clarity, alertness, concentration, and memory; as well as for treating Alzheimer’s disease and dementia. Because of its role in energy production, NADH is also used for improving athletic performance and treating chronic fatigue syndrome (CFS). Some people use NADH for treating high blood pressure, high cholesterol, jet lag, depression, and Parkinson’s disease; opposing alcohol’s effects on the liver; reducing signs of aging; protecting against the side effects of an AIDS drug called zidovudine (AZT).

DEOXYCYTIDINE HYDROCHLORIDE

X8FX60E66D

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Status:

Possibly Marketed Outside US

First approved in 2023

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Deoxycytidine kinase

Conditions:

2′-Deoxycytidine (deoxyC) is one of the deoxy nucleosides, which after phosphorylation to dCTP is used to synthesize DNA via various DNA polymerases or reverse transcriptases. Deoxycytidine is phosphorylated by deoxycytidine kinase (dCK). This enzyme...

catalyzes the initial conversion of the nucleosides deoxyadenosine (dA), deoxyguanosine (dG), and deoxycytidine (dC) into their monophosphate forms, with subsequent phosphorylation to the triphosphate forms performed by additional enzymes.

DISODIUM NICOTINAMIDE ADENINE DINUCLEOTIDE

8295030YNC

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Status:

Possibly Marketed Outside US

First approved in 2011

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

cell redox homeostasis

NAD-dependent deacetylase sirtuin 1

L-lactate dehydrogenase A chain

Alcohol dehydrogenase alpha chain

Nicotinamide adenine nucleotide (NAD) is a cofactor found in all living cells. It exists in oxidized form (NAD+) and reduced form (NADH). NADH is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron...

carrier by being alternately oxidized (NAD+) and reduced (NADH). NADH supplements are used for improving mental clarity, alertness, concentration, and memory; as well as for treating Alzheimer’s disease and dementia. Because of its role in energy production, NADH is also used for improving athletic performance and treating chronic fatigue syndrome (CFS). Some people use NADH for treating high blood pressure, high cholesterol, jet lag, depression, and Parkinson’s disease; opposing alcohol’s effects on the liver; reducing signs of aging; protecting against the side effects of an AIDS drug called zidovudine (AZT).

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