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US Approved OTC

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Investigational

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Primary Target

Sodium channel alpha subunit

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Sodium/potassium-transporting ATPase

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Highest Phase

Approved

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Approval Year

1921

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Unknown

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Condition

Genital warts

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Hyperkalemia

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Molluscum contagiosum

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Nail grooves

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Plane warts

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Treatment Modality

Primary

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CNS Penetrant

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Originator

Davy, H.

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Neuroscience Translational Medicine, Novartis Institutes for Biomedical Research

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Chemical

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CAS

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FDA UNII

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PUBCHEM

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EPA CompTox

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CHEBI

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SENSORY ORGANS

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OPHTHALMOLOGICALS

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OTHER OPHTHALMOLOGICALS

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ATC Level 4

Other ophthalmologicals

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Substance Form

Salts, Hydrates, Esters, etc.

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Showing 1 - 10 of 11 results

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HYDROXIDE ION

9159UV381P

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium/potassium-transporting ATPase

Sodium channel alpha subunit

Conditions:

Molluscum contagiosum

Sodium is the primary cation (positive ion) in extracellular fluids in animals and humans. Sodium ions are necessary for regulation of blood and body fluids, transmission of nerve impulses, heart activity, and certain metabolic functions. Physiologic...

ally, it exists as an ion in the body. Sodium is needed by animals, which maintain high concentrations in their blood and extracellular fluids, but the ion is not needed by plants. The human requirement for sodium in the diet is less than 500 mg per day, which is typically less than a tenth as much as many diets "seasoned to taste. " Most people consume far more sodium than is physiologically needed. For certain people with salt-sensitive blood pressure, this extra intake may cause a negative effect on health.

SELURAMPANEL

7WG1MR7DAR

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Status:

Investigational

Class (Stereo):

CHEMICAL (ACHIRAL)

Selurampanel (previously known as BGG 492), an orally available, AMPA-type glutamate receptor (AMPAR)/kainate receptor (GluK1; GluR5) antagonist was developed by Novartis. It is known that AMPAR antagonism is under development as a novel mechanism of...

action for antiepileptic drugs. Selurampanel was studied in phase II clinical trial for the migraine treatment. However, Proof-of-concept criterion was not met. In addition, the drug also participated in phase II clinical trials in therapy-refractory partial seizures for epilepsy surgery and in patients with chronic subjective tinnitus. Development of selurampanel for all these diseases was discontinued as of September 2017.

POTASSIUM OXIDE

58D606078H

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium/potassium-transporting ATPase

Sodium channel alpha subunit

Conditions:

Molluscum contagiosum

Sodium is the primary cation (positive ion) in extracellular fluids in animals and humans. Sodium ions are necessary for regulation of blood and body fluids, transmission of nerve impulses, heart activity, and certain metabolic functions. Physiologic...

ally, it exists as an ion in the body. Sodium is needed by animals, which maintain high concentrations in their blood and extracellular fluids, but the ion is not needed by plants. The human requirement for sodium in the diet is less than 500 mg per day, which is typically less than a tenth as much as many diets "seasoned to taste. " Most people consume far more sodium than is physiologically needed. For certain people with salt-sensitive blood pressure, this extra intake may cause a negative effect on health.

Sodium hydroxide

55X04QC32I

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium/potassium-transporting ATPase

Sodium channel alpha subunit

Conditions:

Molluscum contagiosum

Sodium is the primary cation (positive ion) in extracellular fluids in animals and humans. Sodium ions are necessary for regulation of blood and body fluids, transmission of nerve impulses, heart activity, and certain metabolic functions. Physiologic...

ally, it exists as an ion in the body. Sodium is needed by animals, which maintain high concentrations in their blood and extracellular fluids, but the ion is not needed by plants. The human requirement for sodium in the diet is less than 500 mg per day, which is typically less than a tenth as much as many diets "seasoned to taste. " Most people consume far more sodium than is physiologically needed. For certain people with salt-sensitive blood pressure, this extra intake may cause a negative effect on health.

SODIUM CATION

LYR4M0NH37

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium/potassium-transporting ATPase

Sodium channel alpha subunit

Conditions:

Molluscum contagiosum

Sodium is the primary cation (positive ion) in extracellular fluids in animals and humans. Sodium ions are necessary for regulation of blood and body fluids, transmission of nerve impulses, heart activity, and certain metabolic functions. Physiologic...

ally, it exists as an ion in the body. Sodium is needed by animals, which maintain high concentrations in their blood and extracellular fluids, but the ion is not needed by plants. The human requirement for sodium in the diet is less than 500 mg per day, which is typically less than a tenth as much as many diets "seasoned to taste. " Most people consume far more sodium than is physiologically needed. For certain people with salt-sensitive blood pressure, this extra intake may cause a negative effect on health.

POTASSIUM FLUORIDE TETRAHYDRATE

1V272UD7M7

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium/potassium-transporting ATPase

Sodium channel alpha subunit

Conditions:

Molluscum contagiosum

Sodium is the primary cation (positive ion) in extracellular fluids in animals and humans. Sodium ions are necessary for regulation of blood and body fluids, transmission of nerve impulses, heart activity, and certain metabolic functions. Physiologic...

ally, it exists as an ion in the body. Sodium is needed by animals, which maintain high concentrations in their blood and extracellular fluids, but the ion is not needed by plants. The human requirement for sodium in the diet is less than 500 mg per day, which is typically less than a tenth as much as many diets "seasoned to taste. " Most people consume far more sodium than is physiologically needed. For certain people with salt-sensitive blood pressure, this extra intake may cause a negative effect on health.

POTASSIUM BIFLUORIDE

880X05W53M

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium/potassium-transporting ATPase

Sodium channel alpha subunit

Conditions:

Molluscum contagiosum

Sodium is the primary cation (positive ion) in extracellular fluids in animals and humans. Sodium ions are necessary for regulation of blood and body fluids, transmission of nerve impulses, heart activity, and certain metabolic functions. Physiologic...

ally, it exists as an ion in the body. Sodium is needed by animals, which maintain high concentrations in their blood and extracellular fluids, but the ion is not needed by plants. The human requirement for sodium in the diet is less than 500 mg per day, which is typically less than a tenth as much as many diets "seasoned to taste. " Most people consume far more sodium than is physiologically needed. For certain people with salt-sensitive blood pressure, this extra intake may cause a negative effect on health.

POTASSIUM FLUORIDE DIHYDRATE

95R1D12HEH

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Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium/potassium-transporting ATPase

Sodium channel alpha subunit

Conditions:

Molluscum contagiosum

Sodium is the primary cation (positive ion) in extracellular fluids in animals and humans. Sodium ions are necessary for regulation of blood and body fluids, transmission of nerve impulses, heart activity, and certain metabolic functions. Physiologic...

ally, it exists as an ion in the body. Sodium is needed by animals, which maintain high concentrations in their blood and extracellular fluids, but the ion is not needed by plants. The human requirement for sodium in the diet is less than 500 mg per day, which is typically less than a tenth as much as many diets "seasoned to taste. " Most people consume far more sodium than is physiologically needed. For certain people with salt-sensitive blood pressure, this extra intake may cause a negative effect on health.

POTASSIUM FLUORIDE

9082WG1G3F

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Search for Structure

Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium/potassium-transporting ATPase

Sodium channel alpha subunit

Conditions:

Molluscum contagiosum

Sodium is the primary cation (positive ion) in extracellular fluids in animals and humans. Sodium ions are necessary for regulation of blood and body fluids, transmission of nerve impulses, heart activity, and certain metabolic functions. Physiologic...

ally, it exists as an ion in the body. Sodium is needed by animals, which maintain high concentrations in their blood and extracellular fluids, but the ion is not needed by plants. The human requirement for sodium in the diet is less than 500 mg per day, which is typically less than a tenth as much as many diets "seasoned to taste. " Most people consume far more sodium than is physiologically needed. For certain people with salt-sensitive blood pressure, this extra intake may cause a negative effect on health.

Potassium hydroxide

WZH3C48M4T

Export Data
Search for Structure

Status:

US Approved OTC

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium/potassium-transporting ATPase

Sodium channel alpha subunit

Conditions:

Molluscum contagiosum

Sodium is the primary cation (positive ion) in extracellular fluids in animals and humans. Sodium ions are necessary for regulation of blood and body fluids, transmission of nerve impulses, heart activity, and certain metabolic functions. Physiologic...

ally, it exists as an ion in the body. Sodium is needed by animals, which maintain high concentrations in their blood and extracellular fluids, but the ion is not needed by plants. The human requirement for sodium in the diet is less than 500 mg per day, which is typically less than a tenth as much as many diets "seasoned to taste. " Most people consume far more sodium than is physiologically needed. For certain people with salt-sensitive blood pressure, this extra intake may cause a negative effect on health.

Showing 1 - 10 of 11 results

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