U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
Investigational
Source:
INN:floxacrine
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

FLOXACRINE, a dihydroacridinedione derivative, is an antimalarial agent. It showed high potency against blood-induced infection of drug-sensitive and drug-resistant lines of Plasmodium berghei in animal models.
Status:
Investigational
Source:
INN:axamozide
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Axamozide is a neuroleptic agent.
Status:
Investigational
Source:
INN:elbanizine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Elbanizine [HWA 214] is an antihistamine which was undergoing preclinical trials with Hoechst Marion Roussel in Germany for the treatment of allergic asthma. Elbanizine does not have such drawbacks as causing drowsiness or being effective only as a prophylactic drug, and could provide advantages over other non-sedative compounds, such as terfenadine and astemizole, in that it is water soluble and thus can be administered through inhalation or through intravenous application.