ELBANIZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H31N5O2
Molecular Weight	445.5566
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC(NCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)=C(C(C)=N1)[N+]([O-])=O

InChI

InChIKey=QMCHYTVPUAJEMM-UHFFFAOYSA-N

InChI=1S/C26H31N5O2/c1-20-19-24(25(31(32)33)21(2)28-20)27-13-14-29-15-17-30(18-16-29)26(22-9-5-3-6-10-22)23-11-7-4-8-12-23/h3-12,19,26H,13-18H2,1-2H3,(H,27,28)

HIDE SMILES / InChI

Molecular Formula	C26H31N5O2
Molecular Weight	445.5566
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://adisinsight.springer.com/drugs/800003288 | https://www.sciencedirect.com/science/article/pii/0223523489900032

Elbanizine [HWA 214] is an antihistamine which was undergoing preclinical trials with Hoechst Marion Roussel in Germany for the treatment of allergic asthma. Elbanizine does not have such drawbacks as causing drowsiness or being effective only as a prophylactic drug, and could provide advantages over other non-sedative compounds, such as terfenadine and astemizole, in that it is water soluble and thus can be administered through inhalation or through intravenous application.

Originator

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:37:08 GMT 2023` Edited by `admin` on `Fri Dec 15 15:37:08 GMT 2023`
Record UNII	S39YD087F9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ELBANIZINE

Official Name

English

1-(2-((2,6-DIMETHYL-3-NITRO-4-PYRIDYL)AMINO)ETHYL)-4-(DIPHENYLMETHYL)PIPERAZINE

Systematic Name

English

elbanizine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578