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Details

Stereochemistry RACEMIC
Molecular Formula C20H13ClF3NO3
Molecular Weight 407.77
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLOXACRINE

SMILES

ON1C2=C(C(=O)CC(C2)C3=CC=C(C=C3)C(F)(F)F)C(=O)C4=C1C=CC(Cl)=C4

InChI

InChIKey=AWHZKKVSUJJVNL-UHFFFAOYSA-N
InChI=1S/C20H13ClF3NO3/c21-13-5-6-15-14(9-13)19(27)18-16(25(15)28)7-11(8-17(18)26)10-1-3-12(4-2-10)20(22,23)24/h1-6,9,11,28H,7-8H2

HIDE SMILES / InChI
Molecular Formula C20H13ClF3NO3
Molecular Weight 407.77
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

FLOXACRINE, a dihydroacridinedione derivative, is an antimalarial agent. It showed high potency against blood-induced infection of drug-sensitive and drug-resistant lines of Plasmodium berghei in animal models.

Originator

Hoechst AG
3

Approval Year

Unknown
149,124

PubMed

Patents

04291034
2
04593027
1
20050002865
228
20100226943
186
6264917
20
6331289
128
WO1996040108A1
3
Substance Class Chemical
Record UNII
V09GC6329G
Record Status Validated (UNII)
Record Version
NIH
NCATS
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