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Originator

Fourcroy, M.M.|Vauquelin, N.L.

4

Pfizer

420

Eli Lilly

239

Merck

238

GlaxoSmithKline

197

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Development Status

Possibly Marketed Outside US

4

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Primary Target

Urate oxidase (mammals)

4

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Approval Year

2016

4

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Condition

Cardiovascular diseases

4

Multiple sclerosis

4

Type 2 diabetes mellitus

4

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Treatment Modality

Diagnostic

4

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CNS Activity

CNS Non-penetrant

4

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Substance Class

Chemical

4

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Code System

CAS

4

ECHA (EC/EINECS)

4

EPA CompTox

4

FDA UNII

4

PUBCHEM

4

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Substance Form

Salts, Hydrates, Esters, etc.

3

Principal Form

1

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Showing 1 - 4 of 4 results

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URIC ACID

268B43MJ25

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Status:

Possibly Marketed Outside US

First approved in 2016

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Urate oxidase (mammals)

Conditions:

Multiple sclerosis

Cardiovascular diseases

Type 2 diabetes mellitus

Uric acid, generated from the metabolism of purines, has proven and emerging roles in human disease. Humans produce large quantities of uric acid. Excess serum accumulation of uric acid can lead to a type of arthritis known as gout. Hyperuricemia may...

increase risk factors for cardiovascular disease. High serum uric acid was associated with higher risk of type 2 diabetes and other diseases.

1H-PURINE-2,6,8(3H)-TRIONE, 7,9-DIHYDRO-, MONOAMMONIUM SALT

524UGG86Q5

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Status:

Possibly Marketed Outside US

First approved in 2016

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Urate oxidase (mammals)

Conditions:

Multiple sclerosis

Cardiovascular diseases

Type 2 diabetes mellitus

Uric acid, generated from the metabolism of purines, has proven and emerging roles in human disease. Humans produce large quantities of uric acid. Excess serum accumulation of uric acid can lead to a type of arthritis known as gout. Hyperuricemia may...

increase risk factors for cardiovascular disease. High serum uric acid was associated with higher risk of type 2 diabetes and other diseases.

DISODIUM URATE

1TX0E9ZJ0W

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Status:

Possibly Marketed Outside US

First approved in 2016

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Urate oxidase (mammals)

Conditions:

Multiple sclerosis

Cardiovascular diseases

Type 2 diabetes mellitus

Uric acid, generated from the metabolism of purines, has proven and emerging roles in human disease. Humans produce large quantities of uric acid. Excess serum accumulation of uric acid can lead to a type of arthritis known as gout. Hyperuricemia may...

increase risk factors for cardiovascular disease. High serum uric acid was associated with higher risk of type 2 diabetes and other diseases.

SODIUM URATE

WA4Q622EWK

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Status:

Possibly Marketed Outside US

First approved in 2016

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Urate oxidase (mammals)

Conditions:

Multiple sclerosis

Cardiovascular diseases

Type 2 diabetes mellitus

Uric acid, generated from the metabolism of purines, has proven and emerging roles in human disease. Humans produce large quantities of uric acid. Excess serum accumulation of uric acid can lead to a type of arthritis known as gout. Hyperuricemia may...

increase risk factors for cardiovascular disease. High serum uric acid was associated with higher risk of type 2 diabetes and other diseases.

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