Dipipanone are indicated for the management of moderate to severe pain in medical and surgical conditions in which morphine may be indicated. Dipipanone is related to methadone and can be substituted for assorted opioids. The severe or irreversible adverse effects of Dipipanone, which give rise to further complications, include hypotension, hypotension, hependence, agranulocytosis, ischemic colitis, generalized chorea, hypersensitivity hepatitis. It may interact badly with monoamine oxidase inhibitors, which are substances found in some antidepressants and other medication.

Amiphenazole, a respiratory stimulant, can be used parenteral and oral. Nicholas Laboratories marketed it under the trade name Daptazole. It was used to treat chronic respiratory failure, by increasing ventilation and by reduction of the pCO2 in some patients. Increased ventilation was brought about by an increase in tidal volume rather than an increase in respiratory rate. In combination with bemegride, amiphenazole was used as an antidote for barbiturate, glutethimide overdose, as well as poisoning from other sedative drugs. Now, this drug is used very rarely, because it replaced by more effective drugs.

Dihydralazine is a compound with antihypertensive properties and is in clinical trials, where is studied its effect on kidney function and hormones in healthy individuals.

Oftasceine is a fluorescent dye or luminescent agent. It was recommended for the use as an effective agent for the blood-retinal barrier integrity studies. It was used to detect drug interactions with multidrug resistance proteins because it is an effective substrate of the multidrug resistance transporter 1P-glycoprotein and the multidrug resistance-related protein. The Oftasceine assay can be used as a quantitative, standardized, inexpensive screening test in a routine clinical laboratory setting. The assay detects both P-glycoprotein and multidrug resistance-associated protein activities, and identifies acute myeloid leukaemia patients with unfavorable therapy responses. It is used in ophthalmic solutions as a staining agent when fitting hydrogel contact lens. The use of a fluorexon dye-impregnated strip (pre-wetted with preservative-free saline) yielded comparable results with a fluorescein strip for assessments of tear film stability based on tear film break-up time.