DIPIPANONE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C24H31NO.ClH
Molecular Weight	385.97
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCC(=O)C(CC(C)N1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=DTXPDSQEMZRBBG-UHFFFAOYSA-N

InChI=1S/C24H31NO.ClH/c1-3-23(26)24(21-13-7-4-8-14-21,22-15-9-5-10-16-22)19-20(2)25-17-11-6-12-18-25;/h4-5,7-10,13-16,20H,3,6,11-12,17-19H2,1-2H3;1H

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Description
Sources: https://www.drugs.com/uk/dipipanone-cyclizine-10-mg-30-mg-tablets-leaflet.html
Curator's Comment: description was created based on several sources, including: http://www.druginfosys.com/drug.aspx?drugcode=252&type=1 | doi: 10.1007/978-3-540-68706-1_1823 | Miller, R.L. (2002) "The Encyclopedia of Addictive Drugs", p.130 Retrieved from https://books.google.ru/books?id=G7As-qawdzMC

Dipipanone are indicated for the management of moderate to severe pain in medical and surgical conditions in which morphine may be indicated. Dipipanone is related to methadone and can be substituted for assorted opioids. The severe or irreversible adverse effects of Dipipanone, which give rise to further complications, include hypotension, hypotension, hependence, agranulocytosis, ischemic colitis, generalized chorea, hypersensitivity hepatitis. It may interact badly with monoamine oxidase inhibitors, which are substances found in some antidepressants and other medication.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pain 614 Sources: https://www.drugs.com/uk/dipipanone-cyclizine-10-mg-30-mg-tablets-leaflet.html	Primary		Not Provided 504	Diconal Approved Use Dipipanone has no officially approved medical usage in the United States, but elsewhere it is used as a powerful pain reliever.

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

The initial dose in all conditions is Dipipanone 10 mg (+ 30 mg Cyclizine) every 6 hours. It is seldom necessary to exceed a dose of 30 mg dipipanone given 6-hourly.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Name

Type

Language

DIPIPANONE HYDROCHLORIDE

Common Name

English

HOECHST-10805

Code

English

DIPIPANONE HCL

Common Name

English

DIPIPANONE HYDROCHLORIDE [MI]

Common Name

English

3-HEPTANONE, 4,4-DIPHENYL-6-(1-PIPERIDINYL)-, HYDROCHLORIDE

Systematic Name

English

DIPIPANONE HYDROCHLORIDE [MART.]

Common Name

English

PIPADONE

Brand Name

English

378C48

Code

English

Dipipanone hydrochloride [WHO-DD]

Common Name

English

4,4-DIPHENYL-6-PIPERIDINO-3-HEPTANONE HYDROCHLORIDE

Systematic Name

English

(±)-DIPIPANONE HYDROCHLORIDE

Common Name

English

HOECHST 10805

Code

English

DIPIPANONE HYDROCHLORIDE, (±)-

Common Name

English

FENPIDON

Brand Name

English

3-HEPTANONE, 4,4-DIPHENYL-6-(1-PIPERIDINYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C67413