DIPIPANONE

Details

Stereochemistry	RACEMIC
Molecular Formula	C24H31NO
Molecular Weight	349.509
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC(=O)C(CC(C)N1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=SVDHSZFEQYXRDC-UHFFFAOYSA-N

InChI=1S/C24H31NO/c1-3-23(26)24(21-13-7-4-8-14-21,22-15-9-5-10-16-22)19-20(2)25-17-11-6-12-18-25/h4-5,7-10,13-16,20H,3,6,11-12,17-19H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C24H31NO
Molecular Weight	349.509
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.drugs.com/uk/dipipanone-cyclizine-10-mg-30-mg-tablets-leaflet.html
Curator's Comment: description was created based on several sources, including: http://www.druginfosys.com/drug.aspx?drugcode=252&type=1 | doi: 10.1007/978-3-540-68706-1_1823 | Miller, R.L. (2002) "The Encyclopedia of Addictive Drugs", p.130 Retrieved from https://books.google.ru/books?id=G7As-qawdzMC

Dipipanone are indicated for the management of moderate to severe pain in medical and surgical conditions in which morphine may be indicated. Dipipanone is related to methadone and can be substituted for assorted opioids. The severe or irreversible adverse effects of Dipipanone, which give rise to further complications, include hypotension, hypotension, hependence, agranulocytosis, ischemic colitis, generalized chorea, hypersensitivity hepatitis. It may interact badly with monoamine oxidase inhibitors, which are substances found in some antidepressants and other medication.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pain 619 Sources: https://www.drugs.com/uk/dipipanone-cyclizine-10-mg-30-mg-tablets-leaflet.html	Primary		Not Provided 511	Diconal Approved Use Dipipanone has no officially approved medical usage in the United States, but elsewhere it is used as a powerful pain reliever.

PubMed

Title	Date	PubMed
Psychotic symptoms after dipipanone.	1978 Aug 26	79851
Prescription of diamorphine, dipipanone and cocaine in England and Wales.	1997 Sep	16203431

Patents

Sample Use Guides

In Vivo Use Guide

The initial dose in all conditions is Dipipanone 10 mg (+ 30 mg Cyclizine) every 6 hours. It is seldom necessary to exceed a dose of 30 mg dipipanone given 6-hourly.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:26:06 GMT 2025` Edited by `admin` on `Mon Mar 31 18:26:06 GMT 2025`
Record UNII	X188638Y2V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIPIPANONE

Official Name

English

IDS-ND-017

Preferred Name

English

4,4-DIPHENYL-6-PIPERIDINO-3-HEPTANONE

Systematic Name

English

ACSCN-9622

Common Name

English

PHENYLPIPERONE

Common Name

English

2-(1-PIPERIDINO)-4,4-DIPHENYL-5-HEPTANONE

Common Name

English

DIPIPANONE [MI]

Common Name

English

PIPERIDYLAMIDONE

Common Name

English

dipipanone [INN]

Common Name

English

DICONAL

Brand Name

English

DL-4,4-DIPHENYL-6-PIPERIDINOHEPTAN-3-ONE

Common Name

English

Dipipanone [WHO-DD]

Common Name

English

6-PIPERIDINO-4,4-DIPHENYLHEPTAN-3-ONE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C241