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Details

Stereochemistry RACEMIC
Molecular Formula C24H31NO.ClH.H2O
Molecular Weight 403.985
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIPIPANONE HYDROCHLORIDE MONOHYDRATE

SMILES

O.Cl.CCC(=O)C(CC(C)N1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=AVDIIYADRQEYFP-UHFFFAOYSA-N
InChI=1S/C24H31NO.ClH.H2O/c1-3-23(26)24(21-13-7-4-8-14-21,22-15-9-5-10-16-22)19-20(2)25-17-11-6-12-18-25;;/h4-5,7-10,13-16,20H,3,6,11-12,17-19H2,1-2H3;1H;1H2

HIDE SMILES / InChI

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C24H31NO
Molecular Weight 349.509
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description
Curator's Comment: description was created based on several sources, including: http://www.druginfosys.com/drug.aspx?drugcode=252&type=1 | doi: 10.1007/978-3-540-68706-1_1823 | Miller, R.L. (2002) "The Encyclopedia of Addictive Drugs", p.130 Retrieved from https://books.google.ru/books?id=G7As-qawdzMC

Dipipanone are indicated for the management of moderate to severe pain in medical and surgical conditions in which morphine may be indicated. Dipipanone is related to methadone and can be substituted for assorted opioids. The severe or irreversible adverse effects of Dipipanone, which give rise to further complications, include hypotension, hypotension, hependence, agranulocytosis, ischemic colitis, generalized chorea, hypersensitivity hepatitis. It may interact badly with monoamine oxidase inhibitors, which are substances found in some antidepressants and other medication.

Originator

Sources: DOI: 10.1039/JR9500002158

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Diconal

Approved Use

Dipipanone has no officially approved medical usage in the United States, but elsewhere it is used as a powerful pain reliever.
PubMed

PubMed

TitleDatePubMed
Patents

Sample Use Guides

The initial dose in all conditions is Dipipanone 10 mg (+ 30 mg Cyclizine) every 6 hours. It is seldom necessary to exceed a dose of 30 mg dipipanone given 6-hourly.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:16:15 GMT 2023
Edited
by admin
on Sat Dec 16 10:16:15 GMT 2023
Record UNII
B06K5XX77E
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIPIPANONE HYDROCHLORIDE MONOHYDRATE
Common Name English
3-HEPTANONE, 4,4-DIPHENYL-6-(1-PIPERIDINYL)-, HYDROCHLORIDE, HYDRATE (1:1:1)
Systematic Name English
3-HEPTANONE, 4,4-DIPHENYL-6-(1-PIPERIDINYL)-, HYDROCHLORIDE, MONOHYDRATE, (±)-
Systematic Name English
Code System Code Type Description
FDA UNII
B06K5XX77E
Created by admin on Sat Dec 16 10:16:15 GMT 2023 , Edited by admin on Sat Dec 16 10:16:15 GMT 2023
PRIMARY
CAS
80894-42-4
Created by admin on Sat Dec 16 10:16:15 GMT 2023 , Edited by admin on Sat Dec 16 10:16:15 GMT 2023
PRIMARY
PUBCHEM
126961355
Created by admin on Sat Dec 16 10:16:15 GMT 2023 , Edited by admin on Sat Dec 16 10:16:15 GMT 2023
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE
PARENT -> SALT/SOLVATE