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Details

Stereochemistry RACEMIC
Molecular Formula C24H31NO.ClH.H2O
Molecular Weight 403.985
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIPIPANONE HYDROCHLORIDE MONOHYDRATE

SMILES

O.Cl.CCC(=O)C(CC(C)N1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=AVDIIYADRQEYFP-UHFFFAOYSA-N
InChI=1S/C24H31NO.ClH.H2O/c1-3-23(26)24(21-13-7-4-8-14-21,22-15-9-5-10-16-22)19-20(2)25-17-11-6-12-18-25;;/h4-5,7-10,13-16,20H,3,6,11-12,17-19H2,1-2H3;1H;1H2

HIDE SMILES / InChI

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C24H31NO
Molecular Weight 349.509
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Dipipanone are indicated for the management of moderate to severe pain in medical and surgical conditions in which morphine may be indicated. Dipipanone is related to methadone and can be substituted for assorted opioids. The severe or irreversible adverse effects of Dipipanone, which give rise to further complications, include hypotension, hypotension, hependence, agranulocytosis, ischemic colitis, generalized chorea, hypersensitivity hepatitis. It may interact badly with monoamine oxidase inhibitors, which are substances found in some antidepressants and other medication.

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Diconal

PubMed

Sample Use Guides

In Vivo Use Guide
The initial dose in all conditions is Dipipanone 10 mg (+ 30 mg Cyclizine) every 6 hours. It is seldom necessary to exceed a dose of 30 mg dipipanone given 6-hourly.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
B06K5XX77E
Record Status Validated (UNII)
Record Version