U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 841 - 850 of 2596 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Silver Bicarbonate is acid salt composed of silver and carbonic acid, that can be used for desalination water purification.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

L-erythro-Sphingosine (also known as erythro-Sphingosine, (+)) – is an inactive isomer from the four possible stereoisomers of sphingosine. This isomer can induce dephosphorylation of pRb protein with EC50 = 5 μM. -erythro-Sphingosine is a weak substrate of ceramidase and has shown competitive inhibition properties.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Tribufos is an organophosphate defoliant used for cotton crops. It is specifically used to defoliate cotton in preparation for machine harvesting. Tribufos inhibits CB1 in vivo, without cholinergic poisoning signs, by 50% at 50 mg/kg intraperitoneally with a recovery half-time of 3-4 days, indicating covalent derivatization.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Racemic RS-4-(4-hydroxyphenyl)-2-butanol (rhododendrol, RD) was used as a topical skin-whitening agent until it was recently reported to induce leukoderma. (-)-Rhododendrol is its R(-)- enantiomer. (-)-Rhododendrol, can be extracted from the leaves of Abies webbiana Lindl., having dendrite elongation inhibition activity in cell lines.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Threo-sphingosine, (+)-, also known as D-threo-sphingosine, is the less active form from all isomers of sphingosine, can inhibit protein kinase C in vitro.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

RO1138452 (also known as CAY10441) is one of the more potent high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor, it antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. RO1138452 is an orally bioavailable compound, demonstrated analgesic activity in rodents.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

There is no information about biological or medical application of ferrous nicotinate (also known as iron dinicotinate)
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Eugenyl glucoside is a product of eugenol glucosylation. Eugenol is the principal chemical component of clove oil, accounting for more than 90%, has been well known for its antioxidant, anti-proliferative, analgesic, local anesthetic, anti-inflammatory, antibacterial, and hair growing effects. Eugenol belongs to the class of essential oil that is generally recognized as safe (GRAS) by Food and Drug Administration. Eugenol is liable to sublimate and has a peculiar smell, its modification is needed for application as a component of hair restorers. Therefore, eugenyl glucoside is being produced by organic synthesis and commercially used as an additive in hair restorers since eugenyl glucoside is gradually degraded into eugenol by the indigeneous microorganisms of human skin and acts as a pro-drug of a hair restorer.
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

Magnesium mandelate is an urinary antiseptic.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

L-threo-beta-hydroxyaspartic acid or β-hydroxy-L- aspartic acid is a glutamate uptake inhibitor and possesses antimicrobial activity against various microorganisms.