Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H27OPS3 |
| Molecular Weight | 314.511 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCSP(=O)(SCCCC)SCCCC
InChI
InChIKey=ZOKXUAHZSKEQSS-UHFFFAOYSA-N
InChI=1S/C12H27OPS3/c1-4-7-10-15-14(13,16-11-8-5-2)17-12-9-6-3/h4-12H2,1-3H3
| Molecular Formula | C12H27OPS3 |
| Molecular Weight | 314.511 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Tribufos is an organophosphate defoliant used for cotton crops. It is specifically used to defoliate cotton in preparation for machine harvesting. Tribufos inhibits CB1 in vivo, without cholinergic poisoning signs, by 50% at 50 mg/kg intraperitoneally with a recovery half-time of 3-4 days, indicating covalent derivatization.
Originator
Sources: https://apvma.gov.au/sites/default/files/publication/14831-tribufos-special-review-report.pdf
Curator's Comment: # Bayer
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets. | 2011-03-28 |
|
| Effects of functionalized fullerenes on bifenthrin and tribufos toxicity to Daphnia magna: Survival, reproduction, and growth rate. | 2010-11 |
|
| Biochemical basis of permethrin resistance in Anopheles arabiensis from Lower Moshi, north-eastern Tanzania. | 2010-07-07 |
|
| Insecticide resistance profiles and synergism in field populations of the German cockroach (Dictyoptera: Blattellidae) from Singapore. | 2010-04 |
|
| Vapor toxicity of three prototype volatile insecticidal compounds to house fly (Diptera: Muscidae). | 2009-11 |
|
| Exploring the molecular basis of insecticide resistance in the dengue vector Aedes aegypti: a case study in Martinique Island (French West Indies). | 2009-10-26 |
|
| Variation in resistance to pyrethroids in Helicoverpa armigera from Benin Republic, West Africa. | 2009-10 |
|
| Identification of pyrethroid resistance associated mutations in the para sodium channel of the two-spotted spider mite Tetranychus urticae (Acari: Tetranychidae). | 2009-10 |
|
| Biochemical mechanisms of methoxyfenozide resistance in the cotton leafworm Spodoptera littoralis. | 2009-07 |
|
| Mechanisms of resistance and cross-resistance to agrochemicals in the fairy shrimp Thamnocephalus platyurus (Crustacea: Anostraca). | 2009-05-05 |
|
| Multi-function oxidases are responsible for the synergistic interactions occurring between repellents and insecticides in mosquitoes. | 2009-04-16 |
|
| Carboxylesterase activity, cDNA sequence, and gene expression in malathion susceptible and resistant strains of the cotton aphid, Aphis gossypii. | 2009-03 |
|
| Resistance mechanisms to mitochondrial electron transport inhibitors in a field-collected strain of Tetranychus urticae Koch (Acari: Tetranychidae). | 2009-02 |
|
| A concentration addition model for the activation of the constitutive androstane receptor by xenobiotic mixtures. | 2009-01 |
|
| The effect of insecticide synergists on the response of scabies mites to pyrethroid acaricides. | 2009 |
|
| Genetic characterization of resistance to deltamethrin in Plutella xylostella (Lepidoptera: Plutellidae) from India. | 2008-12 |
|
| Characterization of a novel high-activity esterase in Tunisian populations of the mosquito Culex pipiens. | 2008-04 |
|
| Household vacuum cleaners vs. the high-volume surface sampler for collection of carpet dust samples in epidemiologic studies of children. | 2008-02-21 |
|
| Selection for resistance to methoxyfenozide and 20-hydroxyecdysone in cells of the beet armyworm, Spodoptera exigua. | 2008-01 |
|
| Levels of insecticide resistance and resistance mechanisms in Aedes aegypti from some Latin American countries. | 2007-12 |
|
| Resistance to malathion in field populations of Ceratitis capitata. | 2007-12 |
|
| Genetics and mechanism of resistance to deltamethrin in a field population of Spodoptera litura (Lepidoptera: Noctuidae). | 2007-10 |
|
| Glutathione S-transferase conjugation of organophosphorus pesticides yields S-phospho-, S-aryl-, and S-alkylglutathione derivatives. | 2007-08 |
|
| Resistance to spinosad in the western flower thrips, Frankliniella occidentalis (Pergande), in greenhouses of south-eastern Spain. | 2007-07 |
|
| Toxicity, synergism, and neurological effects of novel volatile insecticides in insecticide-susceptible and -resistant Drosophila strains. | 2007-04 |
|
| Esterase-mediated bifenthrin resistance in a multiresistant strain of the two-spotted spider mite, Tetranychus urticae. | 2007-02 |
|
| Resistance status of the Colorado potato beetle, Leptinotarsa decemlineata, to endosulfan in East Azarbaijan and Ardabil provinces of Iran. | 2007 |
|
| Complete maternal inheritance of bifenazate resistance in Tetranychus urticae Koch (Acari: Tetranychidae) and its implications in mode of action considerations. | 2006-11 |
|
| Mediation of pyrethroid insecticide toxicity to honey bees (Hymenoptera: Apidae) by cytochrome P450 monooxygenases. | 2006-08 |
|
| Synergism between insecticides permethrin and propoxur occurs through activation of presynaptic muscarinic negative feedback of acetylcholine release in the insect central nervous system. | 2006-07 |
|
| Effects of Piperonyl Butoxide on the Metabolism of DEF S,S,S-Tributyl Phosphorotrithioate) in Fingerling Channel Catfish. | 2006 |
|
| Serine hydrolase targets of organophosphorus toxicants. | 2005-12-15 |
|
| Resistance in the mosquito, Culex quinquefasciatus, and possible mechanisms for resistance. | 2005-11 |
|
| Resistance potential of colorado potato beetle (Coleoptera: Chrysomelidae) to novaluron. | 2005-10 |
|
| Metabolic mechanisms of insecticide resistance in the western flower thrips, Frankliniella occidentalis (Pergande). | 2005-10 |
|
| Chlorpyrifos resistance in mosquito Culex quinquefasciatus. | 2005-09 |
|
| Polymorphisms in a carboxylesterase gene between organophosphate-resistant and -susceptible Aphis gossypii (Homoptera: Aphididae). | 2005-08 |
|
| Blood acylpeptide hydrolase activity is a sensitive marker for exposure to some organophosphate toxicants. | 2005-08 |
|
| Synergism and stability of acetamiprid resistance in a laboratory colony of Plutella xylostella. | 2005-08 |
|
| Platelet-activating factor acetylhydrolase: selective inhibition by potent n-alkyl methylphosphonofluoridates. | 2005-06-01 |
|
| Enhanced esterase gene expression and activity in a malathion-resistant strain of the tarnished plant bug, Lygus lineolaris. | 2004-11 |
|
| Resistance and synergistic effects of insecticides in Bactrocera dorsalis (Diptera: Tephritidae) in Taiwan. | 2004-10 |
|
| Evaluation of mechanisms of azinphos-methyl resistance in the codling moth Cydia pomonella (L.). | 2004-10 |
|
| Effects of insecticides and defoliants applied alone and in combination for control of overwintering boll weevil (Anthonomus grandis; Coleoptera: Curculionidae)--laboratory and field studies. | 2004-09 |
|
| Lysophospholipase inhibition by organophosphorus toxicants. | 2004-05-01 |
|
| Synergism of insecticides provides evidence of metabolic mechanisms of resistance in the obliquebanded leafroller Choristoneura rosaceana (Lepidoptera: Tortricidae). | 2004-05 |
|
| Genetic analysis and cross-resistance spectrum of a laboratory-selected chlorfenapyr resistant strain of two-spotted spider mite (Acari: Tetranychidae). | 2004 |
|
| Cotton defoliant runoff as a function of active ingredient and tillage. | 2003-12-17 |
|
| Temephos resistance in two forms of Aedes aegypti and its significance for the resistance mechanism. | 2003-12 |
|
| Microsomal transformation of organophosphorus pesticides by white rot fungi. | 2003-12 |
Patents
Sample Use Guides
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:51:38 GMT 2025
by
admin
on
Mon Mar 31 20:51:38 GMT 2025
|
| Record UNII |
53075G8GRF
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
EPA PESTICIDE CODE |
74801
Created by
admin on Mon Mar 31 20:51:38 GMT 2025 , Edited by admin on Mon Mar 31 20:51:38 GMT 2025
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
C006863
Created by
admin on Mon Mar 31 20:51:38 GMT 2025 , Edited by admin on Mon Mar 31 20:51:38 GMT 2025
|
PRIMARY | |||
|
m11049
Created by
admin on Mon Mar 31 20:51:38 GMT 2025 , Edited by admin on Mon Mar 31 20:51:38 GMT 2025
|
PRIMARY | Merck Index | ||
|
38737
Created by
admin on Mon Mar 31 20:51:38 GMT 2025 , Edited by admin on Mon Mar 31 20:51:38 GMT 2025
|
PRIMARY | |||
|
201-120-8
Created by
admin on Mon Mar 31 20:51:38 GMT 2025 , Edited by admin on Mon Mar 31 20:51:38 GMT 2025
|
PRIMARY | |||
|
DTXSID1024174
Created by
admin on Mon Mar 31 20:51:38 GMT 2025 , Edited by admin on Mon Mar 31 20:51:38 GMT 2025
|
PRIMARY | |||
|
tribufos
Created by
admin on Mon Mar 31 20:51:38 GMT 2025 , Edited by admin on Mon Mar 31 20:51:38 GMT 2025
|
PRIMARY | |||
|
78-48-8
Created by
admin on Mon Mar 31 20:51:38 GMT 2025 , Edited by admin on Mon Mar 31 20:51:38 GMT 2025
|
PRIMARY | |||
|
668
Created by
admin on Mon Mar 31 20:51:38 GMT 2025 , Edited by admin on Mon Mar 31 20:51:38 GMT 2025
|
PRIMARY | |||
|
5125
Created by
admin on Mon Mar 31 20:51:38 GMT 2025 , Edited by admin on Mon Mar 31 20:51:38 GMT 2025
|
PRIMARY | |||
|
53075G8GRF
Created by
admin on Mon Mar 31 20:51:38 GMT 2025 , Edited by admin on Mon Mar 31 20:51:38 GMT 2025
|
PRIMARY |