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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H14O2
Molecular Weight 166.217
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RHODODENDROL, (-)-

SMILES

C[C@@H](O)CCC1=CC=C(O)C=C1

InChI

InChIKey=SFUCGABQOMYVJW-MRVPVSSYSA-N
InChI=1S/C10H14O2/c1-8(11)2-3-9-4-6-10(12)7-5-9/h4-8,11-12H,2-3H2,1H3/t8-/m1/s1

HIDE SMILES / InChI

Molecular Formula C10H14O2
Molecular Weight 166.217
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Racemic RS-4-(4-hydroxyphenyl)-2-butanol (rhododendrol, RD) was used as a topical skin-whitening agent until it was recently reported to induce leukoderma. (-)-Rhododendrol is its R(-)- enantiomer. (-)-Rhododendrol, can be extracted from the leaves of Abies webbiana Lindl., having dendrite elongation inhibition activity in cell lines.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
(-)-Rhododendrol showed remarkable inhibitory effect on b-hexosaminidase activity at the concentration of 100 uM
Substance Class Chemical
Record UNII
97PTR2F3Z8
Record Status Validated (UNII)
Record Version