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Magnesium lauryl sulfate is used as as lubricant in capsule formulations. Magnesium lauryl sulfate
possesses the lubricating properties of magnesium
stearate but without its waterproofing liability. Magnesium lauryl sulfate is considered safe by FDA.
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
S-enantiomer of rolipram is less active at inhibition of type 4 phosphodiesterase. Displays activity 10-fold less than R-rolipram.
4-Hydroxy-4-(3-hydroxy-1-butenyl)-3,5,5-trimethyl-2-cyclohexen-1-one, (4S,3R)-(E)-(±)- (Blumenol A) is a major secondary metabolite initially isolated from the leaves of Annona glabra L. (Annonaceae), commonly known as pond apple, which is a tropical tree distributed mainly in the Americas and in Southeast Asia, and used in traditional medicine as an insecticide and a parasiticide. Blumenol A was reported to display inhibitory activity against a panel of human solid tumor cell lines
There is no information, related to the pharmacological application of D-gulonic acid. But is known, that it is a component of the herb Centella asiatica, and can form a complexes with tungsten(VI) and molybdenum(VI), in aqueous solutions. In addition, was studied how D-gulonic acid could serve as a immobilization support for mushroom tyrosinase.
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Tenuifoliside a (TFSA) is a bioactive oligosaccharide ester component of Polygala tenuifolia Wild, a traditional Chinese medicine that was used to manage mental disorders effectively. It was found, that TFSA exhibited cytoprotective effects on neuronal cells. Further preclinical and clinical trials evaluating their safety, bio efficacy, and bioavailability are suggested to prove the valuable role of natural drugs in the management of depressive disorders. The strong anti-inflammatory effects of tenuifoliside A were mediated by the inhibition of the NF-κB and MAPK pathways, thus tenuifoliside A can be developed as therapeutic for inflammatory diseases.
There is no information about biological and pharmacological application of lead oxalate.
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
1β-CALCITRIOL is an Impurity B of Calcitriol. Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). 1-epicalcitriol is a potent antagonist of 1,25(OH)2D3-induced intestinal calcium
transport (transcaltachia).
24-Cyclopropyl-1α,3β-BIS(((1,1-Dimethylethyl)dimethylsilyl)oxy)-9,10-secochola-5,7,10(19),22-tetraen-24-ol, (5Z,7E,22E,24S)- is the tert-Butyldimethylsilyl ether conjugate of Calcipotriene (C144200), a vitamin D3 analogue with potential antitumor activities. 24-Cyclopropyl-1α,3β-BIS(((1,1-Dimethylethyl)dimethylsilyl)oxy)-9,10-secochola-5,7,10(19),22-tetraen-24-ol, (5Z,7E,22E,24S)- is used in Calcipotriol synthesis. The physiological and toxicological properties of this compound have not been evaluated.
24R-Calcipotriol (PRI 2202) is an impurity of Calcipotriol. 24R-Calcipotriol shows the strong antiproliferative activity on the human breast cancer cell line MCF-7
Epicaptopril is an impurity of Captopril, which is an orally active angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure. Epicaptopril does not show any inhibition of angiotensin-converting enzyme (ACE), and can be used as negative control in ACE inhibition experiments