U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 571 - 580 of 2596 results

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Methyl cholate is a cholesterol biosynthesis inhibitor. It exhibited inhibitory effect on the later step of cholesterol biosynthesis, indicating that its action mode is different from that of statins that act on the HMG-CoA reductase.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Rebaudioside E is one of the associated glycosides found in the stevia plant. It is generally present in preparations of Steviol glycosides at levels lower than stevioside or Rebaudioside A. Food sweetener. Rebaudioside E is minor component of S. rebaudiana and tastes about 150-200 times sweeter than sucrose and is non-caloric.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Thiosulfite (also known as sulfurothioite) is a salt of the thiosulfurous acid, but the information related to its biological and pharmacological properties is unavailable. Thiosulfurous acid remains one of the least studied sulfur acids.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Tenuazonic acid is one of the major Alternaria mycotoxins commonly found as a natural contaminant in food. Tenuazonic acid contamination has been linked to esophageal cancer in human populations at risk of high exposure. Tenuazonic acid inhibits protein synthesis by suppression at the ribosome. Tenuazonic acid was shown to inhibit 12-O-tetradecanoyl phorbol-13-acetate (TPA) induced ornithine decarboxylase (ODC) activity in a mouse model, and in turn suppressed mouse skin tumor promotion. In addition, this compound has been shown to be a new type of Photosystem II inhibitor.
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Vestitol is an isoflavonoid isolated from Brazilian red propolis with potential anti-inflammatory activity. Vestitol showed inhibitory activity on neutrophil migration induced by different inflammatory stimuli. Its activity is related to inhibition or decrease of the release of the chemokines CXCL1/KC and CXCL2/MIP-2 by resident macrophages, resulting in diminished rolling and adhesion of leukocytes in the mesenteric microcirculation. Vestitol, may have potential therapeutic application to modulate inflammation processes, such as those involved with periodontal diseases.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Manganese Dipropionate is a water soluble crystalline salt composed of manganese and propionate with formula C6H10MnO4. Manganese Dipropionate can be used as drying agents/siccatives for paints/coatings and similar products.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Manganese Oleate is used as a drier in varnishes. Used in the process of synthesis of water-soluble and biocompatible MnO@PVP nanoparticles for MR imaging in vitro and in vivo.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Potassium 1-Naphthaleneacetate is a plant growth regulator, pesticide. Potassium 1-Naphthaleneacetate is an active ingredient of K-Salt Fruit Fix 200. K-SALT FRUIT FIX 200 thins the fruit of apples, pears and certain varieties of citrus and olives to provide an adequate return bloom the following season. K-SALT FRUIT FIX 200 controls preharvest drop of apples and pears leading to a larger harvest and a reduction of losses from windfall and knockdown. The in vitro study showed that Potassium 1-Naphthaleneacetate (NAA-K+) might be effective in the control of Fusarium oxysporum. Exogenous application of NAA-K+ affected both spores and mycelium stages of the fungi. NAA-K+ repressed the expression of brlA and fluG genes. Potassium 1-Naphthaleneacetate's registration has being cancelled by Environmental Protection Agency (EPA).
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Ramipril isopropyl ester is the proline-containing impurity of ramipril, labelled as ramipril Impurity B. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure (hypertension) and congestive heart failure.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Ramipril, (-)- is less active R-enantiomer than S-enantiomer. S-ramipril is angiotensin-converting enzyme (ACE) inhibitor, which is used for the treatment of hypertension.