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Details

Stereochemistry ABSOLUTE
Molecular Formula C44H70O23
Molecular Weight 967.0128
Optical Activity UNSPECIFIED
Defined Stereocenters 26 / 26
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of REBAUDIOSIDE E

SMILES

[H][C@@]8(O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(=O)[C@]2(C)CCC[C@@]3(C)[C@]4([H])CC[C@@]5(C[C@]4(CC5=C)CC[C@]23[H])O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O[C@]7([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O

InChI

InChIKey=RLLCWNUIHGPAJY-SFUUMPFESA-N
InChI=1S/C44H70O23/c1-17-11-43-9-5-22-41(2,7-4-8-42(22,3)40(59)66-38-34(30(55)26(51)20(14-47)62-38)64-36-32(57)28(53)24(49)18(12-45)60-36)23(43)6-10-44(17,16-43)67-39-35(31(56)27(52)21(15-48)63-39)65-37-33(58)29(54)25(50)19(13-46)61-37/h18-39,45-58H,1,4-16H2,2-3H3/t18-,19-,20-,21-,22+,23+,24-,25-,26-,27-,28+,29+,30+,31+,32-,33-,34-,35-,36+,37+,38+,39+,41-,42-,43-,44+/m1/s1

HIDE SMILES / InChI

Molecular Formula C44H70O23
Molecular Weight 967.0128
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 26 / 26
E/Z Centers 0
Optical Activity UNSPECIFIED

Rebaudioside E is one of the associated glycosides found in the stevia plant. It is generally present in preparations of Steviol glycosides at levels lower than stevioside or Rebaudioside A. Food sweetener. Rebaudioside E is minor component of S. rebaudiana and tastes about 150-200 times sweeter than sucrose and is non-caloric.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Minor diterpene glycosides from the leaves of Stevia rebaudiana.
2014 May 23
In vitro metabolism of rebaudioside E under anaerobic conditions: Comparison with rebaudioside A.
2015 Aug
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
Steviol, steviolbioside, Reb A and Reb E (Rebaudioside E), were each dissolved in appropriate solvents to provide a set of 200 mg/mL spiking solutions. These solutions were further diluted 10 with their corresponding vehicle to provide another set of dosing solutions at a target concentration of 20 mg/mL. When spiked to the incubation samples (ie. a 100 dilution) it was anticipated that these solutions would result in the target testing concentrations of 2 mg/mL and 0.2 mg/mL, respectively. Reb E incubated at 0.2 mg/mL was also rapidly metabolized to steviol, with almost all converted to steviol after 16 h of incubation.
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:31:54 UTC 2023
Edited
by admin
on Sat Dec 16 08:31:54 UTC 2023
Record UNII
693TGS3OHR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
REBAUDIOSIDE E
MI  
Common Name English
REBAUDIOSIDE E [MI]
Common Name English
FEMA NO. 4936
Code English
KAUR-16-EN-18-OIC ACID, 13-((2-O-.BETA.-D-GLUCOPYRANOSYL-.BETA.-D-GLUCOPYRANOSYL)OXY)-, 2-O-.BETA.-D-GLUCOPYRANOSYL-.BETA.-D-GLUCOPYRANOSYL ESTER, (4.ALPHA.)-
Common Name English
(-)-REBAUDIOSIDE E
Common Name English
Code System Code Type Description
MERCK INDEX
m9513
Created by admin on Sat Dec 16 08:31:54 UTC 2023 , Edited by admin on Sat Dec 16 08:31:54 UTC 2023
PRIMARY Merck Index
EPA CompTox
DTXSID301019861
Created by admin on Sat Dec 16 08:31:54 UTC 2023 , Edited by admin on Sat Dec 16 08:31:54 UTC 2023
PRIMARY
PUBCHEM
72710721
Created by admin on Sat Dec 16 08:31:54 UTC 2023 , Edited by admin on Sat Dec 16 08:31:54 UTC 2023
PRIMARY
CAS
63279-14-1
Created by admin on Sat Dec 16 08:31:54 UTC 2023 , Edited by admin on Sat Dec 16 08:31:54 UTC 2023
PRIMARY
CHEBI
145018
Created by admin on Sat Dec 16 08:31:54 UTC 2023 , Edited by admin on Sat Dec 16 08:31:54 UTC 2023
PRIMARY
SMS_ID
100000182012
Created by admin on Sat Dec 16 08:31:54 UTC 2023 , Edited by admin on Sat Dec 16 08:31:54 UTC 2023
PRIMARY
GRAS Notification (GRN No.)
823
Created by admin on Sat Dec 16 08:31:54 UTC 2023 , Edited by admin on Sat Dec 16 08:31:54 UTC 2023
PRIMARY
FDA UNII
693TGS3OHR
Created by admin on Sat Dec 16 08:31:54 UTC 2023 , Edited by admin on Sat Dec 16 08:31:54 UTC 2023
PRIMARY
Related Record Type Details
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