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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Arginyl-Glycyl-Aspartic Acid is a tripeptide composed of L-arginine, glycine, and L-aspartic acid, used as a biochemical tool in the study of cellular recognition. Arginylglycylaspartic acid hows great affinity for the integrin receptors and Arg-Gly-Asp tripeptide motif can be used for Peptide-Based Target Drug Delivery of anticancer agents. The tripeptide Arg-Gly-Asp (RGD) is an important protein sequence in the binding of proteins to cell surfaces. The RGD motif was identified in fibronectin, vitronectin, osteopontin, collagens, thrombospondin, fibrinogen, and von Willebrand factor. Many adhesive extracellular matrix, blood, and cell surface proteins recognize the RGD sequence for cell attachment.
Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
Fluorescamine is a compound that is not fluorescent itself but reacts with primary amines to form highly fluorescent products. Because fluorescamine can specifically target the surface amines on proteins, a conformational change of the protein will result in a change in fluorescence. The fluorescent products have an excitation maximum at 390 nm and an emission maximum at 475 nm. These properties make fluorescamine ideal for detecting amino groups, especially in proteins, peptides, and amino acids. It is 10 to 100 times more sensitive in detecting primary amino groups than the ninhydrin reaction. Fluorescamine is also employed as a reporter group in protein chemistry and immunology.
2,5-dimethoxy-3,4-dimethylphenethylamine (also known as 2-CG) is a psychedelic compound, which was first synthesized by Shulgin. There is not much information about its pharmacologic or biologic action because 2-CG have been taken only by Shulgin and a small test group.
There is no information about any biological or pharmacological application of lead chlorate.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Lavendustin C or HDBA (2-hyroxyl-5-(2,5-dihydroxybenzylamino) benzoic acid) is the active pharmacophore of lavendustin A, a tyrosine kinase inhibitor isolated from a butyl acetate extract of Streptomyces griseolavendus.
1-(2-Furoyl)piperazine is the Terazosin impurity (Impurity L). It is used in the synthesis of Piperazine. It was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase.
Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
E-Homocamptothecin, (±)- (also known as BN 80245) is an E-ring modified analog of camptothecin. This compound is more stable than camptothecin, remains a potent inhibitor of both cell growth and topoisomerase I. Homocamptothecin exhibited high in vitro cytotoxicities and good in vivo efficacy, thus that compound could be a promising template for the preparation of improved anticancer agents.
Ethyl trifluoroacetate is the ethyl ester of trifluoroacetic acid. It is used in the preparation of pharmaceutically active molecules.
Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
(±)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) is a selective agonist of AMPA subtype of glutamate receptors. It is used in biological studies as an experimental tool.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
6-Methoxy-2-Naphthylacetic acid (6-MNA), an active metabolite of non-steroidal anti-inflammatory drug nabumetone has long half-life and has the tendency to penetrate well into synovial fluid. 6-MNA is a competitive inhibitor of Cox (cyclooxygenases).