1-(2-FUROYL)PIPERAZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H12N2O2
Molecular Weight	180.2038
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C(N1CCNCC1)C2=CC=CO2

InChI

InChIKey=SADPINFEWFPMEA-UHFFFAOYSA-N

InChI=1S/C9H12N2O2/c12-9(8-2-1-7-13-8)11-5-3-10-4-6-11/h1-2,7,10H,3-6H2

HIDE SMILES / InChI

Molecular Formula	C9H12N2O2
Molecular Weight	180.2038
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/22424148 | https://www.ncbi.nlm.nih.gov/pubmed/833813 | https://www.ncbi.nlm.nih.gov/pubmed/11178831 | Beringer, P., Troy, D.B. (2006) Remington: The Science and Practice of Pharmacy, page 1400, retrieved from: https://books.google.ru/books?id=NFGSSSbaWjwC

1-(2-Furoyl)piperazine is the Terazosin impurity (Impurity L). It is used in the synthesis of Piperazine. It was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Synthesis and identification of the major metabolites of prazosin formed in dog and rat.	1977 Jan	833813

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:35:42 GMT 2023` Edited by `admin` on `Sat Dec 16 08:35:42 GMT 2023`
Record UNII	8AUX72LL1P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-(2-FUROYL)PIPERAZINE

Systematic Name

English

PRAZOSIN RELATED COMPOUND D [USP-RS]

Common Name

English

1-(FURAN-2-YLCARBONYL)PIPERAZINE

Systematic Name

English

N-(FURAN-2-OYL)PIPERAZINE

Systematic Name

English

PRAZOSIN HYDROCHLORIDE IMPURITY D [EP IMPURITY]

Common Name

English

N-(2-FUROYL)PIPERAZINE

Systematic Name

English

1-PENTANONMETHANONE, 2-FURANYL-1-PIPERAZINYL-

Systematic Name

English

(FURAN-2-YL)(PIPERAZIN-1-YL)METHANONE

Systematic Name

English

TERAZOSIN HYDROCHLORIDE DIHYDRATE IMPURITY L [EP IMPURITY]

Common Name

English

Code System Code Type Description

PUBCHEM

550206