4-Methoxymethamphetamine (PMMA, para-Methoxymethamphetamine) is a stimulant and psychedelic drug closely related to the amphetamine-class serotonergic drug para-methoxyamphetamine (PMA). Little is known about the pharmacological properties, metabolism, and toxicity of 4-Methoxymethamphetamine. Because of its structural similarity to para-methoxyamphetamine, which has known toxicity in humans, it is thought to have considerable potential to cause harmful side effects or death in overdose. In the early 2010s, a number of deaths in users of the drug MDMA were linked to misrepresented tablets and capsules of 4-Methoxymethamphetamine. In 2010–2013, a cluster of 29 fatal poisonings related to the toxic designer drug 4-Methoxymethamphetamine was revealed in Norway. The toxicity of PMMA is regarded as substantially higher than for amphetamine, methamphetamine, and MDMA, as indicated by 131 fatal and 31 nonfatal poisonings associated with the abuse of 4-Methoxymethamphetamine worldwide. The toxicity of 4-Methoxymethamphetamine is positively correlated with the 4-Methoxymethamphetamine dose and the blood drug level, but the existing literature indicates that certain human subjects may have an increased risk of 4-Methoxymethamphetamine toxicity. 4-Methoxymethamphetamine, like PMA most likely acts as a selective serotonin releasing agent (SSRA) with weak effects on dopamine and norepinephrine transporters. However, relative to MDMA, it is considerably less effective as a serotonin releaser with properties more akin to a reuptake inhibitor in comparison. It evokes robust hyperthermia while producing only modest hyperactivity and serotonergic neurotoxicity, substantially lower than that caused by MDMA.

13,14-dihydro-prostaglandin E1 (dihydroprostaglandin E1 or 13,14-dihydro-PGE) is a biologically active metabolite of prostaglandin E1. It inhibits adenosine triphosphate (ATP) release and thromboxane generation by human platelets. Besides, the reduced influx of LDL cholesterol into the rabbit aorta after in vivo treatment with 13,14-dihydro-PGE1 is of special interest, since LDL cholesterol accumulation in the arterial wall is considered a key event in atherogenesis.

5-P-Coumaroylquinic acid is a cinnamate ester formed by condensation of the carboxyl group of 4-coumaric acid with the 5-hydroxy group of (-)-quinic acid. It is a naturally occuring compound in coffee, Ixeris sonchifolia and Aloe barbadensis. 5-P Coumaroylquinic acid and related compounds are reported to have antioxidant properties.

KF-38789 is a selective inhibitor of P-selectin-mediated cell adhesion (IC50 = 1.97 uM) that displays no effects on L-selectin- and E-selectin-mediated adhesion. KF-38789 inhibits P-selectin-dependent cell adhesion, superoxide production by human PMN and TG-induced cell migration into the murine peritoneal cavity. It was also identified as a tubulin disruptor.

D-propylhexedrine is an optical isomer of propylhexedrine, a vasoconstrictor stimulating α-adrenergic receptors of the sympathetic nervous system. D-propylhexedrine is proposed to be less potent isomer, it is is less pressor and less excitatory on the central nervous system than is the L-isomer.

Blebbistatin is a small molecule inhibitor discovered in a screen for inhibitors of nonmuscle myosin IIA. Blebbistatin is a specific inhibitor of nonmuscle myosin II, it inhibited contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. (+)-blebbistatin is an inactive enantiomer of (±)-Blebbistatin. (–)-blebbistatin is the active species, with an inhibitory concentration for 50% inhibition (IC50) of 2 uM, whereas (+)-blebbistatin is inactive. (+)-blebbistatin is useful as a negative control for the active enantiomer, (-)-Blebbistatin.

Lumisterol (9beta: 10alpha isomer), a C10 epimer of ergosterol, is part of the vitamin D family of steroid compounds. It is a steroid occurring in fungi and irradiation with ultraviolet rays results in the formation of ergosterol (vitamin D2).

.BETA.-ARTESUNATE is enantiomer of artesunate -- a medication used to treat malaria. β-ARTESUNATE is a prodrug that is rapidly converted to its active form dihydroartemisinin. This process involves hydrolysis of the 4-carbon ester group via plasma esterase enzyme. It is hypothesized that the cleavage of endoperoxide bridge in the pharmacophore of DHA generates reactive oxygen species (ROS), which increases oxidative stress and causes malarial protein damage via alkylation. .BETA.-ARTESUNATE have potential application as anticancer agent.

(22S,23S)-homobrassinolide (also known as isohomobrassinolide) is a member of the plant-derived polyhydroxylated derivatives of 5α-cholestane family of compounds; known as brassinosteroids. It was shown that isohomobrassinolide selectively activates the PI3K/Akt signaling pathway by increasing Akt phosphorylation in vitro.

Adlumidine, an alkaloid present in the d-form, was isolated from the plants: Corydalis thyrsiflora Prain, and Fumaria indica, which are used in herbal medicine.