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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H21N
Molecular Weight 155.2804
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROPYLHEXEDRINE, (R)-

SMILES

CN[C@H](C)CC1CCCCC1

InChI

InChIKey=JCRIVQIOJSSCQD-SECBINFHSA-N
InChI=1S/C10H21N/c1-9(11-2)8-10-6-4-3-5-7-10/h9-11H,3-8H2,1-2H3/t9-/m1/s1

HIDE SMILES / InChI
Molecular Formula C10H21N
Molecular Weight 155.2804
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

D-propylhexedrine is an optical isomer of propylhexedrine, a vasoconstrictor stimulating α-adrenergic receptors of the sympathetic nervous system. D-propylhexedrine is proposed to be less potent isomer, it is is less pressor and less excitatory on the central nervous system than is the L-isomer.

CNS Activity

CNS Active
3913
Curator's Comment: D-propylhexedrine is CNS active in animals. No human data available.

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Agonist
2678
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
The pharmacologic activity of N-methyl-beta-cyclohexyl-isopropylamine hydrochloride.
1947 Apr

Sample Use Guides

In Vivo Use Guide
rats: 20 mg/kg
Route of Administration: Intraperitoneal
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:00:21 GMT 2023
Edited
by admin
on Sat Dec 16 11:00:21 GMT 2023
Record UNII
81UZ68T08H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROPYLHEXEDRINE, (R)-
Common Name English
D-PROPYLHEXEDRINE
Common Name English
(+)-PROPYLHEXEDRINE
Common Name English
CYCLOHEXANEETHANAMINE, N,.ALPHA.-DIMETHYL-, (R)-
Systematic Name English
PROPYLHEXEDRINE, (+)-
Common Name English
PROPYLHEXEDRINE D-FORM [MI]
Common Name English
Code System Code Type Description
PUBCHEM
111165
Created by admin on Sat Dec 16 11:00:21 GMT 2023 , Edited by admin on Sat Dec 16 11:00:21 GMT 2023
PRIMARY
FDA UNII
81UZ68T08H
Created by admin on Sat Dec 16 11:00:21 GMT 2023 , Edited by admin on Sat Dec 16 11:00:21 GMT 2023
PRIMARY
CAS
6556-29-2
Created by admin on Sat Dec 16 11:00:21 GMT 2023 , Edited by admin on Sat Dec 16 11:00:21 GMT 2023
PRIMARY
MERCK INDEX
m9242
Created by admin on Sat Dec 16 11:00:21 GMT 2023 , Edited by admin on Sat Dec 16 11:00:21 GMT 2023
PRIMARY Merck Index
Related Record Type Details
Structure of PROPYLHEXEDRINE
RACEMATE -> ENANTIOMER
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