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Showing 1 - 10 of 234 results

Status:
US Approved Rx (2004)
First approved in 1990

Class (Stereo):
CHEMICAL (RACEMIC)



Ofloxacin is one of a new generation of fluorinated quinolones structurally related to nalidixic acid, primary mechanism of action is inhibition of bacterial DNA gyrase. It is an orally administered broad spectrum antibacterial drug active against mo...
Status:
US Approved Rx (2010)
First approved in 1986

Class (Stereo):
CHEMICAL (ABSOLUTE)



Sulbactam is a β-lactamase inhibitor given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that destroys the antibiotics. Sulbactam in combination with semisynthetic antibiotic ampicillin sodium is indi...
Status:
US Approved Rx (2019)
First approved in 1985

Class (Stereo):
CHEMICAL (ABSOLUTE)



Imipenem is a beta-lactam antibiotic belongings to the subgroup of carbapenems. Imipenem has a broad spectrum of activity against aerobic and anaerobic Gram positive as well as Gram negative bacteria. It is particularly important for its activity aga...
Status:
US Approved Rx (2003)
First approved in 1983

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cefuroxime is a semisynthetic, broad-spectrum, cephalosporin antibiotic. Cefuroxime is a bactericidal agent that acts by inhibition of bacterial cell wall synthesis. Cefuroxime has activity in the presence of some beta-lactamases, both penicillinases...
Status:
US Approved Rx (2007)
First approved in 1978

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cefadroxil is a new semisynthetic cephalosporin with a broad antibacterial spectrum and a high chemotherapeutic potential when administered orally. Many studies have established the efficacy of the administration of once- or twice-daily cefadroxil in...
Status:
US Approved Rx (2015)
First approved in 1959

Class (Stereo):
CHEMICAL (ABSOLUTE)



Demeclocycline hydrochloride is an antibiotic isolated from a mutant strain of Streptomyces aureofaciens. It inhibits protein synthesis by binding with the 30S and possibly the 50S ribosomal subunit(s) of susceptible bacteria. Demeclocycline has anti...
Status:
US Approved Rx (2018)
First marketed in 0652

Class (Stereo):
CHEMICAL (ACHIRAL)



Alcohols exhibit rapid broad-spectrum antimicrobial activity against vegetative bacteria (including mycobacteria), viruses, and fungi but are not sporicidal. They are, however, known to inhibit sporulation and spore germination, but this effect is re...
Status:
US Approved OTC
First approved in 1953

Class (Stereo):
CHEMICAL (ABSOLUTE)



Discovered as natural products from actinomycetes soil bacteria, the tetracyclines were first reported in the scientific literature in 1948. They were noted for their broad spectrum antibacterial activity and were commercialized with clinical success...
Status:
US Approved OTC
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



Magnesium diamide is used as a chemical intermediate. Magnesium diamide is spontaneously combustible. It is toxic by inhalation. Skin or eye contact may cause severe burns.
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Coumermycin is from the aminocoumarin class of antibiotic compounds which acts by inhibiting DNA gyrase. Coumermycin is effective against gram-positive bacteria, but not gram-negative bacteria. Coumermycin its derivatives have been studied since th...