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Showing 1 - 10 of 31 results

Status:
US Approved Rx (2022)
First approved in 1955

Class (Stereo):
CHEMICAL (ABSOLUTE)



Prednisolone is a synthetic adrenocortical steroid drug with predominantly glucocorticoid properties. Some of these properties reproduce the physiological actions of endogenous glucocorticosteroids, but others do not necessarily reflect any of the ad...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



APTO-253 is a novel small molecule that can induce expression of the genes that code for the Krüppel-like factor 4 (KLF4) master transcription factor and for the p21 cell cycle inhibitor protein, and can inhibit expression of the c-Myc oncogene, lead...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Triciribine is a purine analogue which inhibits DNA and protein synthesis, it is a synthetic tricyclic nucleoside which acts as a specific inhibitor of the Akt signaling pathway. It selectively inhibits the phosphorylation and activation of Akt1, -2 ...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



LY-2090314 is a GSK-3alpha and GSK-3beta inhibitor developed by Eli Lilly. Phase 2 clinical trials of LY-2090314 as a signle agenst against acute leukemia did not show clinical benefit. LY-2090314 was studied in combination pemetrexed and carboplatin...
Status:
Investigational

Class (Stereo):
CHEMICAL (RACEMIC)



Edelfosine is a synthetic alkyl-lysophospholipid, a potent immunomodulator and an effective inhibitor of tumor cell proliferation. The cytotoxic effect of edelfosine has been evaluated in a large variety of both tumor (leukemic and solid) and normal ...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pirarubicin is a new kind of anthracene nucleus broad-spectrum antitumor antibiotic. This compound was rapidly incorporated into tumor cells, inhibiting DNA polymerase alpha, DNA topoisomerase II and subsequently DNA synthesis. Inhibition of RNA synt...
structurally diverse
Status:
Possibly Marketed Outside US
First approved in 2012

Class:
STRUCTURALLY DIVERSE



Tetradium ruticarpum (Evodia rutaecarpa) is a plant, which belongs to a genus of 9 species of trees. It is known as Euodia or Bee bee tree in the west because it was classified to the genus Euodia in the ancient literature. The volatile oil of Tetrad...
Status:
US Approved Rx (2022)
First approved in 1955

Class (Stereo):
CHEMICAL (MIXED)



Prednisolone is a synthetic adrenocortical steroid drug with predominantly glucocorticoid properties. Some of these properties reproduce the physiological actions of endogenous glucocorticosteroids, but others do not necessarily reflect any of the ad...
Status:
US Approved Rx (2022)
First approved in 1955

Class (Stereo):
CHEMICAL (ABSOLUTE)



Prednisolone is a synthetic adrenocortical steroid drug with predominantly glucocorticoid properties. Some of these properties reproduce the physiological actions of endogenous glucocorticosteroids, but others do not necessarily reflect any of the ad...
Status:
US Approved Rx (2022)
First approved in 1955

Class (Stereo):
CHEMICAL (ABSOLUTE)



Prednisolone is a synthetic adrenocortical steroid drug with predominantly glucocorticoid properties. Some of these properties reproduce the physiological actions of endogenous glucocorticosteroids, but others do not necessarily reflect any of the ad...