U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 81 - 90 of 472 results

Status:
Possibly Marketed Outside US
Source:
High Potency Multivitamins & Minerals Caplets by Ashbury Research Corporation [Canada]
Source URL:
First approved in 2015
Source:
Vita-Rx Diabetic Vitamin by MAS Management Group Inc.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

There is no information about pharmacological and biological application of vanadium pentoxide (V2O5). However, inhalation of this substance is a toxic for mammalian and repeated exposures to V2O5 containing particles may augment lung carcinogenesis in susceptible individuals through oxidative stress mediated pathways.
Status:
Possibly Marketed Outside US
Source:
Lamwave antimicrobial hand sanitizers gel by Guangzhou Youmei Biotechnology Co., Ltd.
(2020)
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Totarol is a meroterpene, and more precisely a terpenophenolic, a chemical compound that is part terpene and part natural phenol. It is a naturally produced diterpene that is bioactive as (+)-totarol. It was first isolated by McDowell and Esterfield from the heartwood of Podocarpus totara, a yew tree found in New Zealand. Totarol showed good activity against Mycobacterium tuberculosis H(37)Rv (MIC of 73.7 uM). It was also most active against the isoniazid-, streptomycin-, and moxifloxacin-resistant variants (MIC of 38.4, 83.4 and 60 uM, respectively). Totarol demonstrated nematicidal and antifouling activities against Caenorhabditis elegans and Artemia salina, it inhibited Leishmania donovani promastigotes, showed good antimicrobial activity against effluxing strains of Staphylococcus aureus. Totarol inhibits bacterial proliferation by targeting FtsZ and it may be useful as a lead compound to develop an effective antitubercular drug.
Status:
Possibly Marketed Outside US
Source:
Co-Balamin by Home Aide Diagnostics, Inc.
Source URL:
First approved in 2015
Source:
Co-Balamin by Home Aide Diagnostics, Inc.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


UBIQUINOL is a reduced form of coenzyme Q10, a lipid-soluble molecule that consists of an aromatic ring and a 10-unit isoprenoid chain. It is naturally produced by the body. A significant increase in plasma CoQ10 status observed after supplementation in one study suggested that UBIQUINOL is a better supplemental form to enhance the CoQ10 status than ubiquinone (the oxidized form of Q10). UBIQUINOL has also been found to reduce oxidative stress induced by strenuous exercise. Oxidative stress is associated with aging and many chronic diseases, such as cardiovascular diseases, cancers, and cognitive decline. Ubiquinol has furthermore been shown to improve mitochondrial oxidative metabolism in the brain, and cognitive improvement was found as a result of Ubiquinol intake in chronic fatigue syndrome patients. UBIQUINOL is considered safe, but can have side effects such as upper abdominal pain, loss of appetite, nausea, diarrhea and headaches. CoQ10 might make blood-thinning drugs, such as warfarin (Coumadin, Jantoven), less effective. This could increase the risk of a blood clot.
Status:
Possibly Marketed Outside US
First approved in 2015
Source:
P1P Skin Rebirth Cream by Phytos Co., Ltd.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)