U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Showing 1 - 10 of 58 results

Status:
US Approved Rx (2021)
First approved in 1940

Class (Stereo):
CHEMICAL (ABSOLUTE)



Estradiol benzoate is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. As the primary, most potent estrogen hormone produced by the ovaries, estrad...
Status:
US Previously Marketed
First approved in 1940

Class (Stereo):
CHEMICAL (ABSOLUTE)

Mannitol hexanitrate, a sugar alcohol that possesses explosive properties. There are existed mention that this compound had been used for the treatment of hypertension and was effective against an angina attack.
Status:
US Previously Marketed
First approved in 1940

Class (Stereo):
CHEMICAL (ABSOLUTE)



Dihydrotachysterol (DHT) is a synthetic vitamin D analog activated in the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). Dihydrotachysterol is used to treat hypocalcemia, hypoparathy...
Status:
US Previously Marketed
First approved in 1940

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

VINBARBITAL, a barbiturate derivative, is a hypnotic drug. Also, it was used for analgesia and anesthesia in obstetrics.
Status:
US Previously Marketed
First approved in 1940

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
US Previously Marketed
First approved in 1940

Class (Stereo):
CHEMICAL (RACEMIC)



Menadione bisulfite is a water-soluble analog of Vitamin K3. Pharmacologic studies on menadione bisulfate indicad that its toxicity is relatively low. In man, doses approximately ten times as great as those generally recommended for therapeutic use,...
Status:
US Previously Marketed
First approved in 1940

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
US Previously Marketed
First approved in 1940

Class (Stereo):
CHEMICAL (ACHIRAL)



Menadione, a drug belong to class of Vitamin K, is prescribed for the treatment of hemorrhage, vitamin K deficiency, moderate to severe forms of hypoprothrombinaemia in adults and children. Menadione is a synthetic form of vitamin K, a lipid-soluble ...
Status:
US Previously Marketed
First approved in 1940

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
US Previously Marketed
First approved in 1940

Class (Stereo):
CHEMICAL (ACHIRAL)



Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...