Details
Stereochemistry | ACHIRAL |
Molecular Formula | C11H15N2O3.Na |
Molecular Weight | 246.2382 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].CC\C=C(/C)C1(CC)C(=O)NC(=O)[N-]C1=O
InChI
InChIKey=OQLZQQCXUHKXAD-UHDJGPCESA-M
InChI=1S/C11H16N2O3.Na/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;/h6H,4-5H2,1-3H3,(H2,12,13,14,15,16);/q;+1/p-1/b7-6+;
Molecular Formula | C11H16N2O3 |
Molecular Weight | 224.2563 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 1 |
Optical Activity | NONE |
Molecular Formula | Na |
Molecular Weight | 22.9898 |
Charge | 1 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Primary | DELVINAL Approved UseThe best therapeutic results are obtained in patients with psychoneuroses, manic-depressive manic or mixed psychoses, toxic or infectious psychoses—and, to a lesser extent, in patients with involutional melancholia. |
Doses
Dose | Population | Adverse events |
---|---|---|
32 mg single, oral Recommended Dose: 32 mg Route: oral Route: single Dose: 32 mg Sources: |
healthy n = 10 Health Status: healthy Population Size: 10 Sources: |
Other AEs: Epigastric discomfort, Nausea... Other AEs: Epigastric discomfort (2 patients) Sources: Nausea (2 patients) Dizziness (1 patient) Sweating (3 patients) Apprehension (1 patient) Fatigue (3 patients) |
AEs
AE | Significance | Dose | Population |
---|---|---|---|
Apprehension | 1 patient | 32 mg single, oral Recommended Dose: 32 mg Route: oral Route: single Dose: 32 mg Sources: |
healthy n = 10 Health Status: healthy Population Size: 10 Sources: |
Dizziness | 1 patient | 32 mg single, oral Recommended Dose: 32 mg Route: oral Route: single Dose: 32 mg Sources: |
healthy n = 10 Health Status: healthy Population Size: 10 Sources: |
Epigastric discomfort | 2 patients | 32 mg single, oral Recommended Dose: 32 mg Route: oral Route: single Dose: 32 mg Sources: |
healthy n = 10 Health Status: healthy Population Size: 10 Sources: |
Nausea | 2 patients | 32 mg single, oral Recommended Dose: 32 mg Route: oral Route: single Dose: 32 mg Sources: |
healthy n = 10 Health Status: healthy Population Size: 10 Sources: |
Fatigue | 3 patients | 32 mg single, oral Recommended Dose: 32 mg Route: oral Route: single Dose: 32 mg Sources: |
healthy n = 10 Health Status: healthy Population Size: 10 Sources: |
Sweating | 3 patients | 32 mg single, oral Recommended Dose: 32 mg Route: oral Route: single Dose: 32 mg Sources: |
healthy n = 10 Health Status: healthy Population Size: 10 Sources: |
PubMed
Title | Date | PubMed |
---|---|---|
Vinbarbital sodium for obstetric amnesia, analgesia, and anesthesia. | 1946 Mar |
|
Vinbarbital sodium for obstetric amnesia, analgesia and anesthesia; a report of 3,000 cases. | 1948 Sep |
|
An analysis and evaluation of vinbarbital sodium for obstetric amnesia and analgesia. | 1950 Mar |
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 14:16:22 GMT 2023
by
admin
on
Sat Dec 16 14:16:22 GMT 2023
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Record UNII |
BAS6234GZ7
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Record Status |
Validated (UNII)
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Record Version |
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-
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Classification Tree | Code System | Code | ||
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DEA NO. |
2100
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NCI_THESAURUS |
C67084
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125-44-0
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23665569
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BAS6234GZ7
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C77632
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CHEMBL503565
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DBSALT002926
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m985
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PRIMARY | Merck Index | ||
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125758
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