U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 17:23:46 UTC 2021
Edited
by admin
on Sat Jun 26 17:23:46 UTC 2021
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
Z20OC92TDI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ZANIDATAMAB
USAN   INN  
Official Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS ERBB2 (EPIDERMAL GROWTH FACTOR RECEPTOR 2, RECEPTOR TYROSINEPROTEIN KINASE ERBB-2, EGFR2, HER2, HER-2, P185C-ERBB2, NEU, CD340)), HUMANIZED MONOCLONAL ANTIBODY, BIPARATOPIC (TARGETING TWO DIFFERENT NON-OVERLAPP
Common Name English
ZW-25
Code English
ANTI-HER2 BI-SPECIFIC MONOCLONAL ANTIBODY ZW25
Common Name English
ZANIDATAMAB [USAN]
Common Name English
ZANIDATAMAB [INN]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN TYROSINE KINASE RECEPTOR HER2) (HUMAN-MUS MUSCULUS BIPARATOPIC MONOCLONAL ZW25 LIGHT CHAIN VARIABLE REGION FRAGMENT) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 20-AMINO ACID LINKER) FUSION PROTEIN WITH HUMAN-MUS MUSCULUS BIPARA
Common Name English
ZW25
Code English
Classification Tree Code System Code
NCI_THESAURUS C155711
Created by admin on Sat Jun 26 17:23:46 UTC 2021 , Edited by admin on Sat Jun 26 17:23:46 UTC 2021
NCI_THESAURUS C28227
Created by admin on Sat Jun 26 17:23:46 UTC 2021 , Edited by admin on Sat Jun 26 17:23:46 UTC 2021
FDA ORPHAN DRUG 715119
Created by admin on Sat Jun 26 17:23:46 UTC 2021 , Edited by admin on Sat Jun 26 17:23:46 UTC 2021
FDA ORPHAN DRUG 519516
Created by admin on Sat Jun 26 17:23:46 UTC 2021 , Edited by admin on Sat Jun 26 17:23:46 UTC 2021
FDA ORPHAN DRUG 554716
Created by admin on Sat Jun 26 17:23:46 UTC 2021 , Edited by admin on Sat Jun 26 17:23:46 UTC 2021
Code System Code Type Description
FDA UNII
Z20OC92TDI
Created by admin on Sat Jun 26 17:23:46 UTC 2021 , Edited by admin on Sat Jun 26 17:23:46 UTC 2021
PRIMARY
DRUG BANK
DB15471
Created by admin on Sat Jun 26 17:23:46 UTC 2021 , Edited by admin on Sat Jun 26 17:23:46 UTC 2021
PRIMARY
NCI_THESAURUS
C130010
Created by admin on Sat Jun 26 17:23:46 UTC 2021 , Edited by admin on Sat Jun 26 17:23:46 UTC 2021
PRIMARY
INN
10997
Created by admin on Sat Jun 26 17:23:46 UTC 2021 , Edited by admin on Sat Jun 26 17:23:46 UTC 2021
PRIMARY
CAS
2169946-15-8
Created by admin on Sat Jun 26 17:23:46 UTC 2021 , Edited by admin on Sat Jun 26 17:23:46 UTC 2021
PRIMARY
From To
1_24 1_89
1_150 1_224
1_261 2_229
1_264 2_232
1_296 1_356
1_402 1_460
2_23 2_97
2_147 2_203
2_223 3_215
2_264 2_324
2_370 2_428
3_24 3_89
3_135 3_195
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_332
N 2_300
Related Record Type Details
CONJUGATE -> PARENT
TARGET -> INHIBITOR
BINDING
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL