ZANIDATAMAB ZOVODOTIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sun Dec 18 14:54:05 UTC 2022` Edited by `admin` on `Sun Dec 18 14:54:05 UTC 2022`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	HKH2GV9PVO
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ZANIDATAMAB ZOVODOTIN

Official Name

English

zanidatamab zovodotin [INN]

Common Name

English

IMMUNOGLOBULIN HALF-IG G1-KAPPA/SCFV-H-CH2-CH3, ANTI-(HOMO SAPIENS ERBB2 (EPIDERMAL GROWTH FACTOR RECEPTOR 2, RECEPTOR TYROSINE PROTEIN KINASE ERBB-2, EGFR2, HER2, HER-2, P185C-ERBB2, NEU, CD340)), HUMANIZED MONOCLONAL ANTIBODY, BIPARATOPIC (TARGETING TW

Common Name

English

ZW 49 [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN TYROSINE KINASE RECEPTOR HER2) (HUMAN-MUS MUSCULUS BIPARATOPIC MONOCLONAL ZW25 LIGHT CHAIN VARIABLE REGION FRAGMENT) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 20-AMINO ACID LINKER) FUSION PROTEIN WITH HUMAN-MUS MUSCULUS BIPARA

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28227

Created by admin on Sun Dec 18 14:54:05 UTC 2022 , Edited by admin on Sun Dec 18 14:54:05 UTC 2022

FDA ORPHAN DRUG

522616

Created by admin on Sun Dec 18 14:54:05 UTC 2022 , Edited by admin on Sun Dec 18 14:54:05 UTC 2022

NCI_THESAURUS

C155711

Created by admin on Sun Dec 18 14:54:05 UTC 2022 , Edited by admin on Sun Dec 18 14:54:05 UTC 2022

Code System Code Type Description

NCI_THESAURUS

C175879

Created by admin on Sun Dec 18 14:54:05 UTC 2022 , Edited by admin on Sun Dec 18 14:54:05 UTC 2022

PRIMARY

FDA UNII

HKH2GV9PVO

Created by admin on Sun Dec 18 14:54:05 UTC 2022 , Edited by admin on Sun Dec 18 14:54:05 UTC 2022

PRIMARY

INN

11433

Created by admin on Sun Dec 18 14:54:05 UTC 2022 , Edited by admin on Sun Dec 18 14:54:05 UTC 2022

PRIMARY

DRUG BANK

DB15472

Created by admin on Sun Dec 18 14:54:05 UTC 2022 , Edited by admin on Sun Dec 18 14:54:05 UTC 2022

PRIMARY

CAS

2329698-82-8

Created by admin on Sun Dec 18 14:54:05 UTC 2022 , Edited by admin on Sun Dec 18 14:54:05 UTC 2022

PRIMARY

From	To
1_24	1_89
1_150	1_224
1_261	2_229
1_264	2_232
1_296	1_356
1_402	1_460
2_23	2_97
2_147	2_203
2_223	3_215
2_264	2_324
2_370	2_428
3_24	3_89
3_135	3_195

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_332
N	2_300

Related Record Type Details


					7J9Y28299R

RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2

TARGET->CONJUGATED TOXIN

Amount:


					Z20OC92TDI

PARENT -> CONJUGATE

Amount:

Related Record Type Details


					HKH2GV9PVO

ZANIDATAMAB ZOVODOTIN

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL