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Details

Stereochemistry ACHIRAL
Molecular Formula C12H13N5
Molecular Weight 227.2651
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4-METHYL MEIQX

SMILES

CN1C(N)=NC2=C1C(C)=CC3=C2N=C(C)C=N3

InChI

InChIKey=LAZSIJHHPMHKQI-UHFFFAOYSA-N
InChI=1S/C12H13N5/c1-6-4-8-9(15-7(2)5-14-8)10-11(6)17(3)12(13)16-10/h4-5H,1-3H3,(H2,13,16)

HIDE SMILES / InChI

Molecular Formula C12H13N5
Molecular Weight 227.2651
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450.
1990 Jun 1
Reporter gene transgenic mice as a tool for analyzing the molecular mechanisms underlying experimental carcinogenesis.
2001 Mar
Dietary intake of heterocyclic amines, meat-derived mutagenic activity, and risk of colorectal adenomas.
2001 May
Screening for heterocyclic amines in chicken cooked in various ways.
2002 Aug
Effects of soy sauce and sugar on the formation of heterocyclic amines in marinated foods.
2002 Jul
Reactivity and selectivity of the N-acetyl-Glu-P-1, N-acetyl-Glu-P-2, N-acetyl-MeIQx, and N-acetyl-IQx nitrenium ions: comparison to carbocyclic N-arylnitrenium ions.
2002 Jul 10
Development of a short questionnaire to assess the dietary intake of heterocyclic aromatic amines.
2002 Oct
Prevention of heterocyclic amine-induced DNA damage in colon and liver of rats by different lactobacillus strains.
2003 Dec
Effect of high water-holding capacity on the formation of heterocyclic amines in fried beefburgers.
2003 Jul 16
Heterocyclic amines, meat intake, and association with colon cancer in a population-based study.
2003 Mar 1
A prospective study of meat and meat mutagens and prostate cancer risk.
2005 Dec 15
Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study.
2005 Mar
Tobacco smoking and urinary levels of 2-amino-9H-pyrido[2,3-b]indole in men of Shanghai, China.
2007 Aug
Inhibitory effect of fruit extracts on the formation of heterocyclic amines.
2007 Dec 12
Effect of oil marinades with garlic, onion, and lemon juice on the formation of heterocyclic aromatic amines in fried beef patties.
2007 Dec 12
Meat intake, preparation methods, mutagens and colorectal adenoma recurrence.
2007 Sep
Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.
2008 Apr
Meat and meat mutagens and risk of prostate cancer in the Agricultural Health Study.
2008 Jan
Quantitation of 13 heterocyclic aromatic amines in cooked beef, pork, and chicken by liquid chromatography-electrospray ionization/tandem mass spectrometry.
2008 Jan 9
Quantification of heterocyclic aromatic amines in fried meat by HPTLC/UV-FLD and HPLC/UV-FLD: a comparison of two methods.
2008 Jun 25
Binding of heterocyclic aromatic amines by lactic acid bacteria: results of a comprehensive screening trial.
2008 Mar
Intakes of red meat, processed meat, and meat mutagens increase lung cancer risk.
2009 Feb 1
Meat and heterocyclic amine intake, smoking, NAT1 and NAT2 polymorphisms, and colorectal cancer risk in the multiethnic cohort study.
2009 Jul
Intake of meat, meat mutagens, and iron and the risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
2009 Jul 7
Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancer.
2009 Mar 1
Optimized HPLC method for analysis of polar and nonpolar heterocyclic amines in cooked meat products.
2009 May-Jun
Associations between dietary habits and body mass index with gut microbiota composition and fecal water genotoxicity: an observational study in African American and Caucasian American volunteers.
2009 Oct 21
Dietary exposure to heterocyclic amines in high-temperature cooked meat and fish in Malaysia.
2010 Aug
A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association.
2010 Mar 15
Determination of heterocyclic amines in urine samples by capillary liquid chromatography with evaporated light-scattering detection.
2010 May
A review and meta-analysis of prospective studies of red and processed meat intake and prostate cancer.
2010 Nov 2
Association of meat and fat intake with liver disease and hepatocellular carcinoma in the NIH-AARP cohort.
2010 Sep 8
Genotoxicity and induction of DNA damage responsive genes by food-borne heterocyclic aromatic amines in human hepatoma HepG2 cells.
2013 Sep
Substance Class Chemical
Created
by admin
on Thu Jul 06 02:48:20 UTC 2023
Edited
by admin
on Thu Jul 06 02:48:20 UTC 2023
Record UNII
YRA7G7WU6P
Record Status Validated (UNII)
Record Version
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Name Type Language
4-METHYL MEIQX
Common Name English
4,8-DIMEIQX
Common Name English
2-AMINO-3,4,8-TRIMETHYLIMIDAZO(4,5-F)QUINOXALINE
Systematic Name English
3H-IMIDAZO(4,5-F)QUINOXALIN-2-AMINE, 3,4,8-TRIMETHYL-
Systematic Name English
3,4,8-TRIMETHYL-3H-IMIDAZO(4,5-F)QUINOXALIN-2-AMINE
Systematic Name English
2-AMINO-3,4,8-TRIMETHYL-3H-IMIDAZO(4,5-F)QUINOXALINE
Systematic Name English
3,4,8-TRIMETHYLIMIDAZO(4,5-F)QUINOXALIN-2-AMINE
Systematic Name English
Code System Code Type Description
CAS
95896-78-9
Created by admin on Thu Jul 06 02:48:20 UTC 2023 , Edited by admin on Thu Jul 06 02:48:20 UTC 2023
PRIMARY
FDA UNII
YRA7G7WU6P
Created by admin on Thu Jul 06 02:48:20 UTC 2023 , Edited by admin on Thu Jul 06 02:48:20 UTC 2023
PRIMARY
PUBCHEM
104739
Created by admin on Thu Jul 06 02:48:20 UTC 2023 , Edited by admin on Thu Jul 06 02:48:20 UTC 2023
PRIMARY
MESH
C045421
Created by admin on Thu Jul 06 02:48:20 UTC 2023 , Edited by admin on Thu Jul 06 02:48:20 UTC 2023
PRIMARY
EPA CompTox
DTXSID90242018
Created by admin on Thu Jul 06 02:48:20 UTC 2023 , Edited by admin on Thu Jul 06 02:48:20 UTC 2023
PRIMARY
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