Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H13N5 |
| Molecular Weight | 227.2651 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C(N)=NC2=C1C(C)=CC3=C2N=C(C)C=N3
InChI
InChIKey=LAZSIJHHPMHKQI-UHFFFAOYSA-N
InChI=1S/C12H13N5/c1-6-4-8-9(15-7(2)5-14-8)10-11(6)17(3)12(13)16-10/h4-5H,1-3H3,(H2,13,16)
| Molecular Formula | C12H13N5 |
| Molecular Weight | 227.2651 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450. | 1990 Jun 1 |
|
| Potent antimutagenic activity of white tea in comparison with green tea in the Salmonella assay. | 2001 Aug 22 |
|
| Clean-up procedures for the analysis of heterocyclic aromatic amines (aminoazaarenes) from heat-treated meat samples. | 2001 Dec 14 |
|
| Effects of soy sauce and sugar on the formation of heterocyclic amines in marinated foods. | 2002 Jul |
|
| Reactivity and selectivity of the N-acetyl-Glu-P-1, N-acetyl-Glu-P-2, N-acetyl-MeIQx, and N-acetyl-IQx nitrenium ions: comparison to carbocyclic N-arylnitrenium ions. | 2002 Jul 10 |
|
| Development of a short questionnaire to assess the dietary intake of heterocyclic aromatic amines. | 2002 Oct |
|
| Prevention of heterocyclic amine-induced DNA damage in colon and liver of rats by different lactobacillus strains. | 2003 Dec |
|
| Effect of high water-holding capacity on the formation of heterocyclic amines in fried beefburgers. | 2003 Jul 16 |
|
| Heterocyclic amines, meat intake, and association with colon cancer in a population-based study. | 2003 Mar 1 |
|
| Rapid biomonitoring of heterocyclic aromatic amines in human urine by tandem solvent solid phase extraction liquid chromatography electrospray ionization mass spectrometry. | 2004 Aug |
|
| Addition of various carbohydrates to beef burgers affects the formation of heterocyclic amines during frying. | 2004 Dec 15 |
|
| Determination of heterocyclic aromatic amines (HAs) content in samples of household-prepared meat dishes. | 2004 Mar 25 |
|
| Embryonic turkey liver: activities of biotransformation enzymes and activation of DNA-reactive carcinogens. | 2004 Oct |
|
| Quantitation of carcinogenic heterocyclic aromatic amines and detection of novel heterocyclic aromatic amines in cooked meats and grill scrapings by HPLC/ESI-MS. | 2005 Apr 20 |
|
| A prospective study of meat and meat mutagens and prostate cancer risk. | 2005 Dec 15 |
|
| Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study. | 2005 Mar |
|
| Effect of pH on binding of mutagenic heterocyclic amines by the natural biopolymer poly(gamma-glutamic acid). | 2006 Aug 23 |
|
| Meat mutagens and risk of distal colon adenoma in a cohort of U.S. men. | 2006 Jun |
|
| Differential effects of heterocyclic amines on poly(ADP-ribose) polymerase-1 and mono-ADP-ribosyltransferase A. | 2006 Sep |
|
| Dietary mutagen exposure and risk of pancreatic cancer. | 2007 Apr |
|
| Heterocyclic amines in griddled beef steak analysed using a single extract clean-up procedure. | 2007 Apr |
|
| Tobacco smoking and urinary levels of 2-amino-9H-pyrido[2,3-b]indole in men of Shanghai, China. | 2007 Aug |
|
| Inhibitory effect of fruit extracts on the formation of heterocyclic amines. | 2007 Dec 12 |
|
| Effect of oil marinades with garlic, onion, and lemon juice on the formation of heterocyclic aromatic amines in fried beef patties. | 2007 Dec 12 |
|
| Meat intake, preparation methods, mutagens and colorectal adenoma recurrence. | 2007 Sep |
|
| Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. | 2008 Apr |
|
| Meat and meat mutagens and risk of prostate cancer in the Agricultural Health Study. | 2008 Jan |
|
| Quantitation of 13 heterocyclic aromatic amines in cooked beef, pork, and chicken by liquid chromatography-electrospray ionization/tandem mass spectrometry. | 2008 Jan 9 |
|
| Binding of heterocyclic aromatic amines by lactic acid bacteria: results of a comprehensive screening trial. | 2008 Mar |
|
| Intake of meat, meat mutagens, and iron and the risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. | 2009 Jul 7 |
|
| Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancer. | 2009 Mar 1 |
|
| Associations between dietary habits and body mass index with gut microbiota composition and fecal water genotoxicity: an observational study in African American and Caucasian American volunteers. | 2009 Oct 21 |
|
| Dietary exposure to heterocyclic amines in high-temperature cooked meat and fish in Malaysia. | 2010 Aug |
|
| Determination of heterocyclic amines in urine samples by capillary liquid chromatography with evaporated light-scattering detection. | 2010 May |
|
| A review and meta-analysis of prospective studies of red and processed meat intake and prostate cancer. | 2010 Nov 2 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:45:44 UTC 2023
by
admin
on
Fri Dec 15 19:45:44 UTC 2023
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| Record UNII |
YRA7G7WU6P
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| Record Status |
Validated (UNII)
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| Record Version |
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95896-78-9
Created by
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YRA7G7WU6P
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104739
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C045421
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DTXSID90242018
Created by
admin on Fri Dec 15 19:45:44 UTC 2023 , Edited by admin on Fri Dec 15 19:45:44 UTC 2023
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