PEMIGATINIB

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H27F2N5O4
Molecular Weight	487.4991
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN1C(=O)N(CC2=CN=C3NC(CN4CCOCC4)=CC3=C12)C5=C(F)C(OC)=CC(OC)=C5F

InChI

InChIKey=HCDMJFOHIXMBOV-UHFFFAOYSA-N

InChI=1S/C24H27F2N5O4/c1-4-30-21-14(11-27-23-16(21)9-15(28-23)13-29-5-7-35-8-6-29)12-31(24(30)32)22-19(25)17(33-2)10-18(34-3)20(22)26/h9-11H,4-8,12-13H2,1-3H3,(H,27,28)

HIDE SMILES / InChI

Molecular Formula	C24H27F2N5O4
Molecular Weight	487.4991
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Oct 21 20:50:18 UTC 2019` Edited by `admin` on `Mon Oct 21 20:50:18 UTC 2019`
Record UNII	Y6BX7BL23K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PEMIGATINIB

Official Name

English

3-(2,6-DIFLUORO-3,5-DIMETHOXYPHENYL)-1-ETHYL-8-(MORPHOLIN-4-YLMETHYL)-1,3,4,7-TETRAHYDRO-2H-PYRROLO(3',2':5,6)PYRIDO(4,3-D)PYRIMIDIN-2-ONE

Systematic Name

English

INCB-054828

Common Name

English

PEMIGATINIB [USAN]

Common Name

English

FGFR INHIBITOR INCB054828

Common Name

English

PEMIGATINIB [INN]

Common Name

English

PEMIGATINIB [WHO-DD]

Common Name

English

INCB054828

Code

English

2H-PYRROLO(3',2':5,6)PYRIDO(4,3-D)PYRIMIDIN-2-ONE, 3-(2,6-DIFLUORO-3,5-DIMETHOXYPHENYL)-1-ETHYL-1,3,4,7-TETRAHYDRO-8-(4-MORPHOLINYLMETHYL)-

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

624117