FIBROBLAST GROWTH FACTOR RECEPTOR 3

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:44:10 UTC 2023` Edited by `admin` on `Sat Dec 16 11:44:10 UTC 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	L01TYM08QX
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FIBROBLAST GROWTH FACTOR RECEPTOR 3

Common Name

English

JTK4

Common Name

English

FGFR-3

Common Name

English

FGFR3

Common Name

English

Code System Code Type Description

PHAROS

P22607

Created by admin on Sat Dec 16 11:44:11 UTC 2023 , Edited by admin on Sat Dec 16 11:44:11 UTC 2023

PRIMARY

UNIPROT

P22607

Created by admin on Sat Dec 16 11:44:11 UTC 2023 , Edited by admin on Sat Dec 16 11:44:11 UTC 2023

PRIMARY

FDA UNII

L01TYM08QX

Created by admin on Sat Dec 16 11:44:11 UTC 2023 , Edited by admin on Sat Dec 16 11:44:11 UTC 2023

PRIMARY

From	To
1_39	1_87
1_154	1_206
1_253	1_317

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_76
N	1_203
N	1_240
N	1_272
N	1_293
N	1_306

Related Record Type Details


					G6HRD2P839

NINTEDANIB

INHIBITOR -> TARGET


					TN7CUD1NGA

TASURGRATINIB

INHIBITOR -> TARGET

Amount:


					Q5N6P65LLU

Fibroblast growth factor receptor 3 (V555M)

MUTANT->PARENT

Amount:


					PP449XA4BH

LUCITANIB

INHIBITOR -> TARGET

Amount:


					N9B0H171MJ

DERAZANTINIB

INHIBITOR -> TARGET

Amount:


					98BSN6N516

ROGARATINIB

INHIBITOR -> TARGET

Amount:


					E9M363811V

LY-2874455

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					NR9ZYH80Z8

ZOLIGRATINIB

INHIBITOR -> TARGET

Amount:


					Y6BX7BL23K

PEMIGATINIB

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					KTR287FPI7

FIBROBLAST GROWTH FACTOR RECEPTOR 3 (G697C)

DERIVATIVE -> PARENT


					GP2L3N7FIM

LY-3076226

CONJUGATED TOXIN->TARGET

Amount:


					4B93MGE4AL

FUTIBATINIB

INHIBITOR -> TARGET

Amount:


					CEGM9YBNGD

Selpercatinib

INHIBITOR -> TARGET

Comments:

at higher concentrations that were still clinically achievable


					A4055ME1VK

INFIGRATINIB

INHIBITOR -> TARGET


					890E37NHMV

ERDAFITINIB

INHIBITOR -> TARGET

Amount:


					G0Z5E4YTB4

3D-185 FREE BASE

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					Y7HJ4D4CRT

ODM-203

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					2167OG1EKJ

Fexagratinib

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					JMH6YR91PG

VOFATAMAB

INHIBITOR -> TARGET

Amount:


					S3OPE9IA3Q

PRN-1371

INHIBITOR -> TARGET

Amount:


					620C079F3I

RECIFERCEPT

INHIBITOR -> TARGET

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL