Details
Stereochemistry | ACHIRAL |
Molecular Formula | C4H7NO4 |
Molecular Weight | 133.1027 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CNCC(O)=O
InChI
InChIKey=NBZBKCUXIYYUSX-UHFFFAOYSA-N
InChI=1S/C4H7NO4/c6-3(7)1-5-2-4(8)9/h5H,1-2H2,(H,6,7)(H,8,9)
Molecular Formula | C4H7NO4 |
Molecular Weight | 133.1027 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Disodium iminodiacetate is a salt of iminodiacetic acid (IDA). The iminodiacetate anion can act as a tridentate ligand to form a metal complex with two, fused, five-membered chelate rings. Iminodiacetic acid is used to diagnose problems of the liver, gallbladder and bile ducts in an imaging procedure, called as hepatobiliary iminodiacetic acid (HIDA) scan. A nuclear medicine scanner tracks the flow of the tracer from the liver into the gallbladder and small intestine and creates computer images. In addition, iminodiacetate is a part of the iminodiacetate-modified poly-L-lysine dendrimer (IMPLD), a fluorescent bone-imaging agent. IMPLD is used in the diagnosis of bone tumors, or to be used for the delivery of chemotherapy drugs or therapeutic agents. Bones differ from other body tissues in their unique calcium mineral composition, which consists mainly of hydroxyapatite (HA). IDA functionalization could be used as a general approach to bone targeting by increasing affinity for HA, enabling the transport of other molecules or particles to bones.
Approval Year
PubMed
Title | Date | PubMed |
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Kinetics and mechanisms of EDTA photocatalytic degradation with TiO2. | 2001 |
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Acalculous cholecystitis in a two year old. | 2001 Apr-Jun |
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Chromatographic separation of proteins on metal immobilized iminodiacetic acid-bound molded monolithic rods of macroporous poly(glycidyl methacrylate-co-ethylene dimethacrylate). | 2001 Aug 17 |
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Ion chromatography on chelating stationary phases: separation of alkali metals. | 2001 Jul 6 |
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Diagnostic accuracy of 99Tcm-HIDA with cholecystokinin and gallbladder ejection fraction in acalculous gallbladder disease. | 2001 Jun |
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Structural studies of lanthanide (III) complexes with oxydiacetic acid and iminodiacetic acid in aqueous solution by EXAFS. | 2001 Mar 1 |
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Preparation of acetylated pyranoid glycals from glycosyl halides by chromium(II) complexes under aqueous biphasic conditions. | 2001 Nov 21 |
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A novel[2 + 3]cycloaddition reaction: singlet oxygen mediated formation of 1,3-dipole from iminodiacetic acid dimethyl ester and its addition to maleimides. | 2001 Sep 21 |
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Inductively coupled plasma mass spectrometric determination of heavy metals in sea-water samples after pre-treatment with a chelating resin disk by an on-line flow injection method. | 2002 Jun |
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Synthesis and characterization of uranyl compounds with iminodiacetate and oxydiacetate displaying variable denticity. | 2002 May 20 |
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Electrochemiluminescent biosensors array for the concomitant detection of choline, glucose, glutamate, lactate, lysine and urate. | 2003 Dec 30 |
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Use of complexing agents for effective ion-exchange separation of Co(II)/Ni(II) from aqueous solutions. | 2003 Feb |
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Direct chromatographic capture of enzyme from crude homogenate using immobilized metal affinity chromatography on a continuous supermacroporous adsorbent. | 2003 Feb 7 |
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Does this patient have acute cholecystitis? | 2003 Jan 1 |
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Versatile routes to C-2- and C-6-functionalized glucose derivatives of iminodiacetic acid. | 2003 Jan 24 |
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Protease inhibitors: synthesis of bacterial collagenase and matrix metalloproteinase inhibitors incorporating succinyl hydroxamate and iminodiacetic acid hydroxamate moieties. | 2003 Jun |
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Optimization of immobilized metal ion affinity chromatography for single-step purification of recombinant ovine growth hormone expressed in Escherichia coli. | 2003 May 23 |
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Efficient inclusion body processing using chemical extraction and high gradient magnetic fishing. | 2003 May-Jun |
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Immobilized metal-ion chelating capillary microreactor for peptide mapping analysis of proteins by matrix assisted laser desorption/ ionization-time of flight-mass spectrometry. | 2003 Nov |
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Functional and structural study on chelator-induced suppression of S2/S1 FTIR spectrum in photosynthetic oxygen-evolving complex. | 2003 Oct 1 |
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Cd(II) sensing in water using novel aromatic iminodiacetate based fluorescent chemosensors. | 2003 Oct 30 |
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Primary duodenogastric reflux in children and adolescents. | 2003 Sep |
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Hexafluoroacetone as protecting and activating reagent: site-selective functionalization of iminodiacetic acid. | 2004 Dec |
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Alternative quality control for technetium-99m IDA complexes. | 2004 Dec |
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Control of peptide structure and recognition by Fe(III)-induced helix destabilization. | 2004 Dec 8 |
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Therapeutic efficacy of laparoscopic cholecystectomy in the treatment of biliary dyskinesia. | 2004 Feb |
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Modelling of the acid-base properties of natural and synthetic adsorbent materials used for heavy metal removal from aqueous solutions. | 2004 Feb |
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Performance evaluation of two chelating ion-exchange sorbents for the fractionation of labile and inert metal species from aquatic media. | 2004 Jan |
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Ion exchange properties of monolithic and particle type iminodiacetic acid modified silica. | 2004 Jul |
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Immobilization of oriented protein molecules on poly(ethylene glycol)-coated Si(111). | 2004 Jul |
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Solution-phase combinatorial synthesis of nonpeptide bradykinin antagonists. | 2004 Jul 1 |
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Polystyrene monolithic column functionalized with copper-iminodiacetate complex as a stationary phase for open tubular capillary electrochromatography. | 2004 Jul 30 |
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Analysis of myoglobin adsorption to Cu(II)-IDA and Ni(II)-IDA functionalized Langmuir monolayers by grazing incidence neutron and X-ray techniques. | 2004 Mar 30 |
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Chemical extraction and direct adsorptive purification of recombinant human antigen Ro52. | 2004 May |
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A new bis(3-hydroxy-4-pyridinone)-IDA derivative as a potential therapeutic chelating agent. Synthesis, metal-complexation and biological assays. | 2004 Nov 7 |
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Isolation and growth characteristics of an EDTA-degrading member of the alpha-subclass of Proteobacteria. | 2004 Oct |
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High-buffering capacity, hydrolytically stable, low-pI isoelectric membranes for isoelectric trapping separations. | 2004 Oct |
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Purification and identification of water-soluble phosphopeptides from cheese using Fe(III) affinity chromatography and mass spectrometry. | 2004 Oct 20 |
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Protein surface-assisted enhancement in the binding affinity of an inhibitor for recombinant human carbonic anhydrase-II. | 2004 Sep 8 |
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Purification of a catalase from Thermus thermophilus via IMAC chromatography: effect of the support. | 2004 Sep-Oct |
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Measurement of Wee kinase activity. | 2005 |
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Arsenic speciation in water samples containing high levels of copper: removal of copper interference affecting arsine generation by continuous flow solid phase chelation. | 2005 Apr |
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Aqua(2,2'-bi-1H-imidazole)chlorocopper(II) chloro(iminodiacetato)copper(II) monohydrate. | 2005 Jan |
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Speciation of chromium(III) and cobalt(III) (amino)carboxylate complexes using capillary electrophoresis. | 2005 Jan 1 |
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Multivalent carbocyanine molecular probes: synthesis and applications. | 2005 Jan-Feb |
|
A luminescent receptor with affinity for N-terminal histidine in peptides in aqueous solution. | 2005 Mar 16 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:12:19 GMT 2023
by
admin
on
Fri Dec 15 18:12:19 GMT 2023
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Record UNII |
XQM2L81M8Z
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Record Status |
Validated (UNII)
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Record Version |
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8897
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24786
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C008109
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18467
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205-555-4
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IMINODIACETIC ACID
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2852
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m6229
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142-73-4
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DTXSID2027098
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XQM2L81M8Z
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SALT/SOLVATE -> PARENT |
Related Record | Type | Details | ||
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
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Related Record | Type | Details | ||
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ACTIVE MOIETY |