Details
Stereochemistry | ACHIRAL |
Molecular Formula | C4H5NO4.2Na |
Molecular Weight | 177.0663 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[Na+].[O-]C(=O)CNCC([O-])=O
InChI
InChIKey=HAXVIVNBOQIMTE-UHFFFAOYSA-L
InChI=1S/C4H7NO4.2Na/c6-3(7)1-5-2-4(8)9;;/h5H,1-2H2,(H,6,7)(H,8,9);;/q;2*+1/p-2
Molecular Formula | Na |
Molecular Weight | 22.9898 |
Charge | 1 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C4H5NO4 |
Molecular Weight | 131.0868 |
Charge | -2 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Disodium iminodiacetate is a salt of iminodiacetic acid (IDA). The iminodiacetate anion can act as a tridentate ligand to form a metal complex with two, fused, five-membered chelate rings. Iminodiacetic acid is used to diagnose problems of the liver, gallbladder and bile ducts in an imaging procedure, called as hepatobiliary iminodiacetic acid (HIDA) scan. A nuclear medicine scanner tracks the flow of the tracer from the liver into the gallbladder and small intestine and creates computer images. In addition, iminodiacetate is a part of the iminodiacetate-modified poly-L-lysine dendrimer (IMPLD), a fluorescent bone-imaging agent. IMPLD is used in the diagnosis of bone tumors, or to be used for the delivery of chemotherapy drugs or therapeutic agents. Bones differ from other body tissues in their unique calcium mineral composition, which consists mainly of hydroxyapatite (HA). IDA functionalization could be used as a general approach to bone targeting by increasing affinity for HA, enabling the transport of other molecules or particles to bones.
Approval Year
PubMed
Title | Date | PubMed |
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Determination of trace alkaline earth metals in brines using chelation ion chromatography with an iminodiacetic acid bonded silica column. | 2001 Jan 12 |
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Sensitive and selective ion chromatographic method for the determination of trace beryllium in water samples. | 2001 Mar 2 |
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Dimeric W3SO3 cluster complexes: synthesis, characterization, and potential applications as X-ray contrast agents. | 2001 Mar 26 |
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Determination of silver speciation in natural waters. 2. Binding strength of silver ligands in surface freshwaters. | 2001 May 15 |
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Comparison of histidine-tag capture chemistries for purification following chemical extraction. | 2002 Apr 12 |
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The effect of erythromycin on bile excretion and proximal small bowel motility following divided gastric bypass surgery: a prospective randomized placebo-controlled trial. | 2002 Dec |
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Development of column-pretreatment chelating resins for matrix elimination/multi-element determination by inductively coupled plasma-mass spectrometry. | 2002 Dec |
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Steps toward high specific activity labeling of biomolecules for therapeutic application: preparation of precursor [(188)Re(H(2)O)(3)(CO)(3)](+) and synthesis of tailor-made bifunctional ligand systems. | 2002 Jul-Aug |
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Synthesis and characterization of uranyl compounds with iminodiacetate and oxydiacetate displaying variable denticity. | 2002 May 20 |
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Versatile routes to C-2- and C-6-functionalized glucose derivatives of iminodiacetic acid. | 2003 Jan 24 |
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Nickel and copper complexes of a chelating methacrylate sorbent in the purification of chitinases and specific immunoglobulin G1 by immobilized metal ion affinity chromatography. | 2003 Jan 3 |
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Influence of the morphology of poly(EGDMA-co-HEMA) on the chemical modifications and retention of O-phosphothreonine. | 2003 Jan 31 |
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A comparative study of two chelating ion-exchange resins for the removal of chromium(III) from aqueous solution. | 2003 Jun 27 |
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Optimization of immobilized metal ion affinity chromatography for single-step purification of recombinant ovine growth hormone expressed in Escherichia coli. | 2003 May 23 |
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Efficient inclusion body processing using chemical extraction and high gradient magnetic fishing. | 2003 May-Jun |
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Cd(II) sensing in water using novel aromatic iminodiacetate based fluorescent chemosensors. | 2003 Oct 30 |
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Surface grafting of glycidyl methacrylate on silica gel and polyethylene beads. | 2003 Sep |
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Hexafluoroacetone as protecting and activating reagent: site-selective functionalization of iminodiacetic acid. | 2004 Dec |
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Alternative quality control for technetium-99m IDA complexes. | 2004 Dec |
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Performance evaluation of two chelating ion-exchange sorbents for the fractionation of labile and inert metal species from aquatic media. | 2004 Jan |
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Solution-phase combinatorial synthesis of nonpeptide bradykinin antagonists. | 2004 Jul 1 |
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Preparation of an iminodiacetic acid-modified capillary and its performance in capillary liquid chromatography and immobilized metal chelate affinity capillary electrophoresis. | 2004 Jun 18 |
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Analysis of myoglobin adsorption to Cu(II)-IDA and Ni(II)-IDA functionalized Langmuir monolayers by grazing incidence neutron and X-ray techniques. | 2004 Mar 30 |
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Arsenic speciation in water samples containing high levels of copper: removal of copper interference affecting arsine generation by continuous flow solid phase chelation. | 2005 Apr |
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Aqua(2,2'-bi-1H-imidazole)chlorocopper(II) chloro(iminodiacetato)copper(II) monohydrate. | 2005 Jan |
|
Spacer-based selectivity in the binding of "two-prong" ligands to recombinant human carbonic anhydrase I. | 2005 Mar 8 |
Substance Class |
Chemical
Created
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admin
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Edited
Fri Dec 15 19:48:23 GMT 2023
by
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on
Fri Dec 15 19:48:23 GMT 2023
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Record UNII |
Q2K1N8RVKE
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Record Status |
Validated (UNII)
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Record Version |
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Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |