Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H12FN5O3 |
| Molecular Weight | 269.2324 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=NC2=C(N=CN2[C@H]3C[C@H](F)[C@@H](CO)O3)C(=O)N1
InChI
InChIKey=RTJUXLYUUDBAJN-KVQBGUIXSA-N
InChI=1S/C10H12FN5O3/c11-4-1-6(19-5(4)2-17)16-3-13-7-8(16)14-10(12)15-9(7)18/h3-6,17H,1-2H2,(H3,12,14,15,18)/t4-,5+,6+/m0/s1
| Molecular Formula | C10H12FN5O3 |
| Molecular Weight | 269.2324 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Enhanced in vitro inhibition of HIV-1 replication by 3'-fluoro-3'-deoxythymidine compared to several other nucleoside analogs. | 1988 Dec |
|
| Inhibition of duck hepatitis B virus replication by 2',3'-dideoxy-3'-fluoroguanosine in vitro and in vivo. | 1996 Mar |
|
| Profound antiviral effect of oral administration of MIV-210 on chronic hepadnaviral infection in a woodchuck model of hepatitis B. | 2009 Sep |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 17:37:54 UTC 2023
by
admin
on
Sat Dec 16 17:37:54 UTC 2023
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| Record UNII |
UU109JJU0U
|
| Record Status |
Validated (UNII)
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| Record Version |
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| Name | Type | Language | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C97452
Created by
admin on Sat Dec 16 17:37:55 UTC 2023 , Edited by admin on Sat Dec 16 17:37:55 UTC 2023
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| Code System | Code | Type | Description | ||
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9105
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UU109JJU0U
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C90784
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135431817
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300000036985
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92562-88-4
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DTXSID90239044
Created by
admin on Sat Dec 16 17:37:55 UTC 2023 , Edited by admin on Sat Dec 16 17:37:55 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET ORGANISM->INHIBITOR |
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PRODRUG -> METABOLITE ACTIVE |
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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