Approval Year
| Substance Class |
Structurally Diverse
Created
by
admin
on
Edited
Fri Dec 15 16:02:23 GMT 2023
by
admin
on
Fri Dec 15 16:02:23 GMT 2023
|
| Source Materials Class | ORGANISM |
| Source Materials Type | VIRUS |
| Organism Family | Hepadnaviridae |
| Organism Genus | Orthohepadnavirus |
| Organism Species | hepatovirus b |
| Author | NONE |
| Part | WHOLE |
| Record UNII |
77H9EM77P7
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
Download
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|---|---|---|---|---|
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Systematic Name | English | ||
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Systematic Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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SUB25281
Created by
admin on Fri Dec 15 16:02:23 GMT 2023 , Edited by admin on Fri Dec 15 16:02:23 GMT 2023
|
PRIMARY | |||
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77H9EM77P7
Created by
admin on Fri Dec 15 16:02:23 GMT 2023 , Edited by admin on Fri Dec 15 16:02:23 GMT 2023
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PRIMARY | |||
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1427211
Created by
admin on Fri Dec 15 16:02:23 GMT 2023 , Edited by admin on Fri Dec 15 16:02:23 GMT 2023
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PRIMARY | RxNorm | ||
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C14215
Created by
admin on Fri Dec 15 16:02:23 GMT 2023 , Edited by admin on Fri Dec 15 16:02:23 GMT 2023
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PRIMARY | |||
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10407
Created by
admin on Fri Dec 15 16:02:23 GMT 2023 , Edited by admin on Fri Dec 15 16:02:23 GMT 2023
|
PRIMARY | |||
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77H9EM77P7
Created by
admin on Fri Dec 15 16:02:23 GMT 2023 , Edited by admin on Fri Dec 15 16:02:23 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
BLOCKS VIRAL ENTRY BY BINDING TO SODIUM/BILE ACID COTRANSPORTER
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INHIBITOR->TARGET ORGANISM |
EC50
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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VACCINE ANTIGEN->TARGET ORGANISM |
T-cell antigen
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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VACCINE ANTIGEN->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
EC50
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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VACCINE ANTIGEN->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
Median 50% effective concentration (EC50) values across all genotypes were 10–33 nM
versus 17 nM (genotype D reference). Prevents nucleic acid incorporation into capsid.
EC50
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VACCINE ANTIGEN->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
Inhibits capsid assembly
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INFRASPECIFIC -> PARENT ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
HBV DNA. Highly selective for HBV.
IC50
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INHIBITOR->TARGET ORGANISM |
inhibition of hepatitis B virus (HBV) capsid assembly
EC50
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INHIBITOR->TARGET ORGANISM |
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VACCINE ANTIGEN->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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