Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H25FN6O6 |
| Molecular Weight | 440.4261 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)[C@H](N)C(=O)O[C@@H](C)C(=O)OC[C@H]1O[C@H](C[C@@H]1F)N2C=NC3=C2NC(N)=NC3=O
InChI
InChIKey=MPGXKIZZTFGTLP-HGCLJGPKSA-N
InChI=1S/C18H25FN6O6/c1-7(2)12(20)17(28)30-8(3)16(27)29-5-10-9(19)4-11(31-10)25-6-22-13-14(25)23-18(21)24-15(13)26/h6-12H,4-5,20H2,1-3H3,(H3,21,23,24,26)/t8-,9-,10+,11+,12-/m0/s1
| Molecular Formula | C18H25FN6O6 |
| Molecular Weight | 440.4261 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Potent and selective activity of 3'-azido-2,6-diaminopurine-2',3'-dideoxyriboside, 3'-fluoro-2,6-diaminopurine-2',3'-dideoxyriboside, and 3'-fluoro-2',3'-dideoxyguanosine against human immunodeficiency virus. | 1988 Mar |
|
| Inhibition of duck hepatitis B virus replication by 2',3'-dideoxy-3'-fluoroguanosine in vitro and in vivo. | 1996 Mar |
|
| In vitro activity of structurally diverse nucleoside analogs against human immunodeficiency virus type 1 with the K65R mutation in reverse transcriptase. | 2005 Mar |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 19:49:29 GMT 2023
by
admin
on
Sat Dec 16 19:49:29 GMT 2023
|
| Record UNII |
4GVR2JJD4R
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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135525384
Created by
admin on Sat Dec 16 19:49:29 GMT 2023 , Edited by admin on Sat Dec 16 19:49:29 GMT 2023
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PRIMARY | |||
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4GVR2JJD4R
Created by
admin on Sat Dec 16 19:49:29 GMT 2023 , Edited by admin on Sat Dec 16 19:49:29 GMT 2023
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1001670-19-4
Created by
admin on Sat Dec 16 19:49:29 GMT 2023 , Edited by admin on Sat Dec 16 19:49:29 GMT 2023
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PRIMARY |
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|---|---|---|---|---|
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METABOLITE ACTIVE -> PRODRUG |
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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