Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | 2C18H25FN6O6.H2O4S |
| Molecular Weight | 978.931 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 10 / 10 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OS(O)(=O)=O.CC(C)[C@H](N)C(=O)O[C@@H](C)C(=O)OC[C@H]1O[C@H](C[C@@H]1F)N2C=NC3=C2NC(N)=NC3=O.CC(C)[C@H](N)C(=O)O[C@@H](C)C(=O)OC[C@H]4O[C@H](C[C@@H]4F)N5C=NC6=C5NC(N)=NC6=O
InChI
InChIKey=HEZFRXSHHXMERI-BXQUBGNASA-N
InChI=1S/2C18H25FN6O6.H2O4S/c2*1-7(2)12(20)17(28)30-8(3)16(27)29-5-10-9(19)4-11(31-10)25-6-22-13-14(25)23-18(21)24-15(13)26;1-5(2,3)4/h2*6-12H,4-5,20H2,1-3H3,(H3,21,23,24,26);(H2,1,2,3,4)/t2*8-,9-,10+,11+,12-;/m00./s1
| Molecular Formula | H2O4S |
| Molecular Weight | 98.078 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C18H25FN6O6 |
| Molecular Weight | 440.4261 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Profound antiviral effect of oral administration of MIV-210 on chronic hepadnaviral infection in a woodchuck model of hepatitis B. | 2009-09 |
|
| In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2',3'-dideoxy-3'-fluoroguanosine. | 2006-03 |
|
| In vitro activity of structurally diverse nucleoside analogs against human immunodeficiency virus type 1 with the K65R mutation in reverse transcriptase. | 2005-03 |
|
| Ribavirin and mycophenolic acid potentiate the activity of guanine- and diaminopurine-based nucleoside analogues against hepatitis B virus. | 2000-11 |
|
| Inhibition of duck hepatitis B virus replication by 2',3'-dideoxy-3'-fluoroguanosine in vitro and in vivo. | 1996-03 |
|
| Enhanced in vitro inhibition of HIV-1 replication by 3'-fluoro-3'-deoxythymidine compared to several other nucleoside analogs. | 1988-12 |
|
| Potent and selective activity of 3'-azido-2,6-diaminopurine-2',3'-dideoxyriboside, 3'-fluoro-2,6-diaminopurine-2',3'-dideoxyriboside, and 3'-fluoro-2',3'-dideoxyguanosine against human immunodeficiency virus. | 1988-03 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 21:13:31 GMT 2025
by
admin
on
Wed Apr 02 21:13:31 GMT 2025
|
| Record UNII |
WGP76XJ723
|
| Record Status |
Validated (UNII)
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| Record Version |
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WGP76XJ723
Created by
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171390271
Created by
admin on Wed Apr 02 21:13:31 GMT 2025 , Edited by admin on Wed Apr 02 21:13:31 GMT 2025
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1328880-69-8
Created by
admin on Wed Apr 02 21:13:31 GMT 2025 , Edited by admin on Wed Apr 02 21:13:31 GMT 2025
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> SALT/SOLVATE |
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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